Evidence map›Paper›PMID 41036689›Full record

ArticleEarly intervention in psychiatry2025

Borderline Personality Disorder or First-Episode Psychosis? Challenges in Assessing Psychotic Features in Early Intervention: A Case Report.

Mie Sedoc Jørgensen, Stephen Fitzgerald Austin, Ole Jakob Storebø, Stig Poulsen, Sune Bo, Emma Beck, Erik Simonsen

Abstract readCase Reports
In one paragraph

Article in Early intervention in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mie Sedoc JørgensenPsychiatric Research Unit, Mental Health Services, Region Zealand, Slagelse, Denmark.ORCID https://orcid.org/0000-0003-3320-1231
Stephen Fitzgerald AustinMental Health Services, Region Zealand East, Roskilde, Denmark.ORCID https://orcid.org/0000-0001-5988-0565
Ole Jakob StorebøPsychiatric Research Unit, Mental Health Services, Region Zealand, Slagelse, Denmark.
Stig PoulsenDepartment of Psychology, University of Copenhagen, Copenhagen, Denmark.
Sune BoDepartment of Psychology, University of Copenhagen, Copenhagen, Denmark.
Emma BeckPrivate Practice, Roskilde, Denmark.
Erik SimonsenMental Health Services, Region Zealand East, Roskilde, Denmark.

Funding

Department of Health and Medical Sciences, University of CopenhagenHealth Scientific Research Fund of Region Zealand (HSRF-RZ)TrygFonden, Department of Child and Adolescent Psychiatry
6 · The paper itself

Abstract

introductionAdolescence is a crucial period for the onset of both borderline personality disorder (BPD) and first-episode psychosis. Although transient stress-related paranoid ideation and dissociative symptoms are one of the diagnostic criteria for BPD, determining when these psychotic features progress to early-stage schizophrenia remains unclear.

methodsTwo case studies aimed to explore the challenges in assessing and following up on psychotic features in BPD over time. Two adolescent girls aged 14 and 15 were initially diagnosed with BPD using semi-structured clinical interviews for DSM-IV personality disorder. Five years later, symptom development was explored using comprehensive diagnostic interviews.

resultsBoth cases exhibited lapses in reality testing at baseline, interpreted as transient and stress-related symptoms. The first case illustrated the difficulties in distinguishing normative magical and imaginative thinking in youth from odd beliefs or bizarre fantasies and preoccupations, emphasizing the need for age-adapted and elaborate, detailed phenomenological assessment of the content, duration and frequency of these experiences and their impact on functioning. The second case demonstrated the progression of psychotic features from adolescence into early adulthood and the challenge of judging whether these features crossed the threshold to psychosis.

conclusionBoth cases underscore the need for clinical training regarding differential diagnostics and management of psychotic features when present in early manifestations of BPD. This gap in care presents a missed opportunity for inclusion of patients in targeted early intervention programs for first-episode psychosis. We propose the implementation of a continuous monitoring strategy in BPD with psychotic features.

Indexed as

Borderline Personality DisorderEarly Medical InterventionPsychotic DisordersAdolescentDiagnosis, DifferentialEarly DiagnosisFemaleHumansassessmentborderline personality disordercase reportfirst‐episode psychosis

Identifiers

PMID41036689
PMCPMC12489974

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.