Evidence map›Paper›PMID 41036371›Full record

SynthesisOpen veterinary journal2025

Effects of vitamin E supplementation on sow gestation: a meta-analysis.

Ni Wayan Helpina Widyasanti, Sari Yanti Hayanti, Cecep Hidayat, I Putu Cahyadi Putra, Jonathan Anugrah Lase, Ragil Angga Prastiya, Surya Surya, Maureen Chrisye Hadiatry, Marchie Astrid da Costa, Nandari Dyah Suretno and 4 more

Abstract readMeta-Analysis
In one paragraph

Synthesis in Open veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Effects ofAnimals : an open access journal from MDPI · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ni Wayan Helpina WidyasantiFaculty of Veterinary Medicine, Udayana University, Denpasar, Indonesia.
Sari Yanti HayantiResearch Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency of The Republic of Indonesia (BRIN), Cibinong Sciences Center, Cibinong, Indonesia.
Cecep HidayatResearch Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency of The Republic of Indonesia (BRIN), Cibinong Sciences Center, Cibinong, Indonesia.
I Putu Cahyadi PutraFaculty of Veterinary Medicine, Udayana University, Denpasar, Indonesia.
Jonathan Anugrah LaseResearch Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency of The Republic of Indonesia (BRIN), Cibinong Sciences Center, Cibinong, Indonesia.
Ragil Angga PrastiyaDepartement of Health, Medicine, and Life Sciences, Faculty of Health, Medicine, and Life Sciences (FIKKIA), Universitas Airlangga, Surabaya, Indonesia.
Surya SuryaResearch Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency of The Republic of Indonesia (BRIN), Cibinong Sciences Center, Cibinong, Indonesia.
Maureen Chrisye HadiatryResearch Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency of The Republic of Indonesia (BRIN), Cibinong Sciences Center, Cibinong, Indonesia.
Marchie Astrid da CostaResearch Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency of The Republic of Indonesia (BRIN), Cibinong Sciences Center, Cibinong, Indonesia.
Nandari Dyah SuretnoResearch Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency of The Republic of Indonesia (BRIN), Cibinong Sciences Center, Cibinong, Indonesia.
Reny Debora TambunanResearch Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency of The Republic of Indonesia (BRIN), Cibinong Sciences Center, Cibinong, Indonesia.
Franciscus Rudi Prasetyo HantoroResearch Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency of The Republic of Indonesia (BRIN), Cibinong Sciences Center, Cibinong, Indonesia.
Susana Insusila Watyning RakhmaniResearch Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency of The Republic of Indonesia (BRIN), Cibinong Sciences Center, Cibinong, Indonesia.
Yenny YusrianiResearch Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency of The Republic of Indonesia (BRIN), Cibinong Sciences Center, Cibinong, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Vitamin E is an antioxidant that plays a crucial function in the reproductive processes of pigs. Aim: This study evaluated the reproductive efficacy of ɑ-tocopherol or vitamin E supplementation in pregnant sows. Methods: Twenty-one articles from 1977 to 2021 were included in the database. There were eight parameters observed, such as concentration in the serum during gestation, colostrum concentration, number of piglets per litter at birth, number of stillborn piglets, number of piglets born alive, litter weight at birth, weight of each piglet at birth, and piglet serum concentration on day 1. The data were analyzed using the PROC MIXED procedure in SAS version 9.1. Results: Vitamin E administration in sows led to a statistically significant rise in the level of α-tocopherol in the serum of both sows during gestation and the serum of piglets on the first day after birth. The injection of vitamin E did not yield a statistically significant effect on the observed variables, including an increase in the number of pigs per litter at birth, stillborn piglets, pigs born alive, litter weight at birth, vitamin E levels in colostrum, dan the weight of piglets at delivery. Conclusions: Vitamin E supplements are advisable for female pigs to increase the concentration of α-tocopherol in serum throughout pregnancy and enhance α-tocopherol levels in the serum of piglets on the first day after birth.

Indexed as

AntioxidantsVitamin Ealpha-TocopherolAnimalsColostrumDietary SupplementsFemaleLitter SizePregnancySwinealpha-TocopherolAntioxidantsVitamin EAntioxidantɑ-TocopherolPregnancySwine.

Identifiers

PMID41036371
PMCPMC12483425

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.