ArticleFrontiers in neurology2025
Thrombo-pathologic features and prognosis of acute ischemic stroke patients treated with remedial stent implantation.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Remedial stenting (RS) is a crucial therapy for people with acute ischemic stroke (AIS) if blood flow cannot be maintained following thrombus removal. Still, not much is known about the thrombus composition in these patients. Therefore, this study aims to compare the thrombo-pathological features of patients with AIS undergoing RS and non-remedial stenting (NRS) and to examine the correlation between thrombus composition and prognosis in patients with RS. Methods: This study included 89 patients with AIS who underwent endovascular thrombolysis. Patients were classified into RS and NRS groups based on modified thrombolysis in cerebral infarction (mTICI) scores. The primary thrombus components were identified using ICH and HE staining. The study also examined the association between thrombus components and patient prognosis. Results: The levels of neutrophil extracellular traps (NET) [0.41 (0.34, 0.61) vs. 0.36 (0.31, 0.40)], CD163 [0.31 (0.23, 0.38) vs. 0.21 (0.18, 0.23)], and C-reactive protein (CRP) [0.33 (0.26, 0.42) vs. 0.27 (0.22, 0.33)] were significantly higher in the RS group compared to the NRS group. After adjusting for other variables, both von Willebrand factor (VWF) and CD163 were associated with poor prognosis in stented patients ( Conclusions: Thrombi from the RS and NRS groups exhibited variations in NET, CD163, and CRP levels. In the RS group, poor patient prognosis strongly correlates with VWF and CD163 levels in the thrombi.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.