Evidence map›Paper›PMID 41036225›Full record

ArticleFrontiers in cellular and infection microbiology2025

Proteome changes during

Joachim Müller, Javier Regidor-Cerrillo, David Arranz-Solís, Sophie Braga-Lagache, Anne-Christine Uldry, Manfred Heller, Rafael Calero-Bernal, Andrew Hemphill, Luis Miguel Ortega-Mora

Abstract read
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In one paragraph

Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Joachim Müller *Institute of Parasitology, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Javier Regidor-Cerrillo *SALUVET-INNOVA, Animal Health Department, Faculty of Veterinary Sciences, Complutense University of Madrid, Madrid, Spain.
David Arranz-SolísSALUVET, Animal Health Department, Faculty of Veterinary Sciences, Complutense University of Madrid, Madrid, Spain.
Sophie Braga-LagacheProteomics and Mass Spectrometry Core Facility, Department for BioMedical Research (DBMR), University of Bern, Bern, Switzerland.
Anne-Christine UldryProteomics and Mass Spectrometry Core Facility, Department for BioMedical Research (DBMR), University of Bern, Bern, Switzerland.
Manfred HellerProteomics and Mass Spectrometry Core Facility, Department for BioMedical Research (DBMR), University of Bern, Bern, Switzerland.
Rafael Calero-BernalSALUVET, Animal Health Department, Faculty of Veterinary Sciences, Complutense University of Madrid, Madrid, Spain.
Andrew HemphillInstitute of Parasitology, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Luis Miguel Ortega-MoraSALUVET, Animal Health Department, Faculty of Veterinary Sciences, Complutense University of Madrid, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Rapid Methods: The differential proteomes of six recently obtained archetypal European Results: Among these isolates, 2.3% and 10.2% of proteins were differentially or constantly abundant when comparing low and high passage numbers. Constant proteins included components involved in essential cellular processes such as energy metabolism or protein synthesis, many of them identified as drug and vaccine targets. Interestingly, differentially abundant proteins were clearly linked to phenotypic changes associated to Conclusion: Our results highlight the changes at the proteomic level that take place in recently obtained isolates after

Indexed as

Adaptation, PhysiologicalProteomeProtozoan ProteinsToxoplasmaAnimalsChlorocebus aethiopsChromatography, LiquidMass SpectrometryProteomicsVero CellsProteomeProtozoan Proteinsbradyzoiteculture adaptationdrug- vaccine targetsproteomeToxoplasma gondiivirulence factors

Identifiers

PMID41036225
PMCPMC12479500

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.