Evidence map›Paper›PMID 41036189›Full record

ArticleFrontiers in nutrition2025

The relationship between nutritional status and prealbumin levels in children with loss of appetite and iron deficiency: a prospective cross-sectional study.

Ömer Okuyan, Sinem Durmus, Hafize Uzun

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Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ömer OkuyanDepartment of Pediatrics, Istanbul Atlas University Hospital, Faculty of Medicine, Istanbul Atlas University, Istanbul, Türkiye.
Sinem DurmusDepartment of Medical Biochemistry, Faculty of Medicine, İzmir Katip Çelebi University, İzmir, Türkiye.
Hafize UzunDepartment of Medical Biochemistry, Faculty of Medicine, Istanbul Atlas University, Istanbul, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Prealbumin, a hepatic protein with a short half-life, has emerged as a sensitive biomarker for assessing nutritional status. This study aimed to evaluate the relationship between nutritional status and prealbumin levels in children experiencing loss of appetite due to iron deficiency and to compare the diagnostic value of prealbumin with established nutritional indices. Methods: A total of 260 children aged 2-15 years were enrolled and categorized into four groups: control ( Results: Prealbumin levels were significantly lower in all patient groups than in controls ( Conclusion: While appetite loss is a clinically reported symptom, reduced prealbumin levels reflect the underlying nutritional impact of this condition. Prealbumin is a sensitive and reliable biomarker for assessing nutritional deterioration associated with both appetite loss and iron deficiency in children and outperforms commonly used nutritional indices. Its use may improve early recognition and management of nutritional risk in pediatric populations. Further research is needed to explore the diagnostic and prognostic value of nutritional indices (CONUT, PNI, and NRI) in children.

Indexed as

childrencontrolling nutritional statusloss of appetitenutritional risk indexprealbuminprognostic nutritional index

Identifiers

PMID41036189
PMCPMC12479313

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.