Evidence map›Paper›PMID 41036095›Full record

ArticleUrology case reports2025

Hyperferritinemia revealing renal carcinoma with TFE3 gene translocation: a rare case report.

Ezékéel Judicaël Bocovo, Yannick Jean Rodrigue Pingdwendé Traoré, Quentin Caspar, Cristina Daniliuc, Christelle Ahomadégbé, Romulus Takin, François Nollez

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In one paragraph

Article in Urology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Ezékéel Judicaël BocovoDepartment of Pathology and Cytopathology, Yalgado Ouédraogo University Hospital, Ouagadougou, Burkina Faso.
Yannick Jean Rodrigue Pingdwendé TraoréDepartment of Urology, Yalgado Ouédraogo University Hospital, Ouagadougou, Burkina Faso.
Quentin CasparDepartment of Pathology and Cytopathology, Troyes Hospital Center, Troyes, France.
Cristina DaniliucDepartment of Pathology and Cytopathology, Troyes Hospital Center, Troyes, France.
Christelle AhomadégbéDepartment of Pathology and Cytopathology, Troyes Hospital Center, Troyes, France.
Romulus TakinDepartment of Pathology and Cytopathology, Troyes Hospital Center, Troyes, France.
François NollezDepartment of Pathology and Cytopathology, Troyes Hospital Center, Troyes, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present the case of a 39-year-old man who was hospitalized due to hyperferritinemia. During the etiological workup, an abdominal-pelvic MRI incidentally revealed a left renal cystic mass classified as Bosniak III. A partial left nephrectomy was performed. Histologically, we observed malignant tumor proliferation with a polymorphic architecture. Immunohistochemistry revealed that the tumor cells weakly expressed keratins (AE1/AE3), but not carbonic anhydrase IX. Due to these unusual findings and the patient's young age, fluorescence in situ hybridization (FISH) was performed, revealing a rearrangement of the TFE3 gene in over 80 % of the tumor cells.

Indexed as

FISHHyperferritinemiaMiTFRenal carcinomaTFE3

Identifiers

PMID41036095
PMCPMC12481126

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