Evidence map›Paper›PMID 41036012›Full record

ArticleOpen veterinary journal2025

Effectiveness of papaya leaf extract (

Viski Fitri Hendrawan, Alsya Pritama, Aulia Firmawati, Intan Firdha Olien Noor Al Ichsan, Ertika Fitri Lisnanti

Abstract read
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In one paragraph

Article in Open veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Viski Fitri HendrawanDepartment of Veterinary Reproduction, Faculty of Veterinary Medicine, Brawijaya University, Malang, Indonesia.
Alsya PritamaStudents of Undergraduate, Faculty of Veterinary Medicine, Brawijaya University, Malang, Indonesia.
Aulia FirmawatiDepartment of Veterinary Reproduction, Faculty of Veterinary Medicine, Brawijaya University, Malang, Indonesia.
Intan Firdha Olien Noor Al IchsanStudents of Undergraduate, Faculty of Veterinary Medicine, Brawijaya University, Malang, Indonesia.
Ertika Fitri LisnantiProgram of Animal Husbandry, Faculty of Agriculture, Universitas Islam Kadiri, Kediri, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Natural contraception is an affordable and accessible alternative to synthetic hormonal methods. One strategy for controlling overpopulation involves the use of plant-based agents that possess antifertility properties. Aim: This study aimed to investigate the antifertility effects of papaya ( Methods: This study included six female albino rats ( Results: The P2 dosage group demonstrated a 3-day increase in estrus cycle length and a 56.97% decrease in ovarian ER-β expression. This shows that the group can prolong the estrous cycle with a diestrus phase predominance and diminish ovarian ER-β expression, making it an anti-infertility drug. Conclusion: The P2 group best prolongs the estrous cycle of female white rats. The expression of ovarian ER-β decreases.

Indexed as

CaricaEstrogen Receptor betaEstrous CycleOvaryPlant ExtractsAnimalsFemalePlant LeavesRatsEstrogen Receptor betaPlant ExtractsAntifertilityER-βExtract of papaya leafVaginal Swab

Identifiers

PMID41036012
PMCPMC12483521

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.