Evidence map›Paper›PMID 41035995›Full record

ArticleOpen veterinary journal2025

Growth progression and hematobiochemical dynamics in broiler chickens treated with antibiotic, probiotic, and acidifier.

Md Mominul Islam, Md Saiful Islam, Khaled Mahmud Sujan, Mohammad Alam Miah

Abstract read
In one paragraph

Article in Open veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Md Mominul IslamDepartment of Physiology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Md Saiful IslamDepartment of Biochemistry and Molecular Biology, Faculty of Agriculture, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Khaled Mahmud SujanDepartment of Physiology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Mohammad Alam MiahDepartment of Physiology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh, Bangladesh.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Feed additive supplementation for weight gain is a recent trend in poultry farming. Antibiotics, probiotics, and acidifiers are commonly administered to improve weight gain and health status. Understanding their specific effects on growth and hematobiochemical parameters is essential for broiler production optimization. Aim: This research aimed to investigate the effects of antibiotic, probiotic, and acidifier treatments on broiler growth progression and hematobiochemical alterations. Methods: Eighty 12-day-old broiler chicks were randomly divided into four groups: Group A (control), Group B (antibiotic-treated), Group C (probiotic-treated), and Group D (acidifier-treated). The respective feed additives were administered to groups B, C, and D, while group A received a standard diet without additives. Body weights were recorded weekly until day 33, and blood samples were collected for hematological and biochemical analysis on the final day. Results: A significant increase in body weight was observed for all treatment groups compared with the control group across all observation days. The antibiotic-treated group showed a substantial increase in the total erythrocyte count, hemoglobin, and packed cell volume compared with the other groups. The total cholesterol level was significantly reduced in the probiotic- and acidifier-treated groups, and the triglyceride level was remarkably decreased in the acidifier-treated group. Furthermore, high-density lipoprotein levels were significantly increased in the acidifier-treated group and decreased in the antibiotic-treated group. However, low-density lipoprotein was significantly increased in the treated groups. Additionally, the aspartate aminotransferase level was notably elevated in the antibiotic- and acidifier-treated groups, while all treatment groups showed a significant increase in alanine aminotransferase level compared to the control. Conclusion: Antibiotic, probiotic, and acidifier supplementation significantly enhanced weight gain in broilers compared with the control group. Among the treatments, antibiotics notably improved hematological parameters, whereas probiotics and acidifiers positively influenced lipid profiles. Overall, these feed additives had beneficial effects on growth and selected biochemical parameters, with varying impacts on hematological values.

Indexed as

Anti-Bacterial AgentsChickensProbioticsAnimal FeedAnimalsDietDietary SupplementsMaleWeight GainAnti-Bacterial AgentsAcidifierAntibioticGrowth performanceHematobiochemical profileProbiotic

Identifiers

PMID41035995
PMCPMC12483384

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.