Evidence map›Paper›PMID 41035968›Full record

ArticleOpen veterinary journal2025

Therapeutic potential of L-Carnitine in improving adenine-induced hematological abnormalities in rats: A preclinical pharmacological study.

Waleed Khaled Y Albahadly, Mohammed Jasim Jawad, Mohammed Ibrahim Rasool, Haider Falih ShamikhAl-Saedi, Asia Ali Hamza

Abstract read
In one paragraph

Article in Open veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Waleed Khaled Y AlbahadlyDepartment of Pharmacology and Toxicology, College of Pharmacy, University of Karbala, Karbala, Iraq.
Mohammed Jasim JawadDepartment of Pharmacology and Toxicology, College of Pharmacy, University of Karbala, Karbala, Iraq.
Mohammed Ibrahim RasoolDepartment of Pharmacology and Toxicology, College of Pharmacy, University of Karbala, Karbala, Iraq.
Haider Falih ShamikhAl-SaediDepartment of Pharmacology, College of Pharmacy, University of Al-Ameed, Karbala, Karbala, Iraq.
Asia Ali HamzaDepartment of Clinical Laboratory Sciences, University of Al-kafeel, Karbala, Iraq.

Funding

College of Pharmacy, University of Karbala
6 · The paper itself

Abstract

Background: Adenine is a naturally occurring purine essential for life, but its excess intake can cause metabolic disturbances leading to cardiovascular complications, renal stones, gout, fatigue, and anemia. Aim: This study aimed to investigate the potential hematological protective effects of L-Carnitine in rats subjected to adenine-induced toxicity. Methods: Twenty-four adult male Wistar rats were randomly assigned to four groups ( Results: Rats treated with adenine alone showed a significant reduction in red blood cells, hemoglobin, packed cell volume, and platelet counts and a marked increase in white blood cell levels ( Conclusion: L-Carnitine exhibited a hematoprotective effect against adenine-induced toxicity, highlighting its potential therapeutic role in managing metabolic disturbances associated with purine overload.

Indexed as

AdenineCarnitineHematologic DiseasesAnimalsMaleRandom AllocationRatsRats, WistarAdenineCarnitineAdenineHematologyL-Carnitine

Identifiers

PMID41035968
PMCPMC12483437

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.