Evidence map›Paper›PMID 41035923›Full record

ArticleCase reports in transplantation2025

Hepatitis E Virus Infection in a Liver Transplant Recipient Presenting With Late-Onset Acute Rejection and Treated With Ribavirin.

Daffolyn Rachael Fels Elliott, Jwan Alallaf, Devin Shrock, Katie L Dennis, Ryan M Taylor, Maura F O'Neil

Abstract readCase Reports
In one paragraph

Article in Case reports in transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daffolyn Rachael Fels ElliottDepartment of Pathology and Laboratory Medicine, University of Kansas Health System, Kansas City, Kansas, USA.ORCID https://orcid.org/0000-0001-9966-4197
Jwan AlallafDepartment of Pathology and Laboratory Medicine, University of Kansas Health System, Kansas City, Kansas, USA.ORCID https://orcid.org/0009-0008-6014-2752
Devin ShrockDepartment of Pathology and Laboratory Medicine, University of Kansas Health System, Kansas City, Kansas, USA.ORCID https://orcid.org/0009-0004-9373-6611
Katie L DennisDepartment of Pathology and Laboratory Medicine, University of Kansas Health System, Kansas City, Kansas, USA.ORCID https://orcid.org/0000-0003-0994-8933
Ryan M TaylorDivision of Gastroenterology/Hepatology, Department of Internal Medicine, University of Kansas Health System, Kansas City, Kansas, USA.ORCID https://orcid.org/0009-0003-6851-9087
Maura F O'NeilDepartment of Pathology and Laboratory Medicine, University of Kansas Health System, Kansas City, Kansas, USA.ORCID https://orcid.org/0000-0001-9740-1027

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis E virus (HEV) is increasingly recognized as a cause of allograft hepatitis in transplant recipients. Persistent HEV infection is often asymptomatic with nonspecific findings on liver biopsy, requiring high clinical awareness to order viral testing. We present a challenging case of HEV allograft hepatitis that presented with increasing liver enzymes and subtle biopsy findings of hepatocyte apoptosis and mitosis, diagnosed 1 month after treatment of acute rejection. Viral testing was positive for HEV IgM and HEV RNA, consistent with acute HEV infection. The patient was treated with a 12-week course of ribavirin. Based on this index case, we reviewed whether liver allograft biopsies with apoptosis were associated with viral detection at our institution during a 6-year period (

Indexed as

acute rejectionallograft hepatitishepatitis E virusliver transplant

Identifiers

PMID41035923
PMCPMC12483739

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.