ArticleCase reports in anesthesiology2025
Safe Administration of Octenidine in a Surgical Patient With Documented Severe Chlorhexidine Anaphylaxis: A Case Report and Review of the Current Evidence.
Article in Case reports in anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Safe Administration of Octenidine in a Surgical Patient With Documented Severe Chlorhexidine Anaphylaxis: A Case Report and Review of the Current Evidence.Case reports in anesthesiology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chlorhexidine is one of the most widely used antiseptics worldwide. Owing to its extensive use, reports of chlorhexidine allergic reactions are increasing. In cases of severe chlorhexidine anaphylaxis, the potential for cross-reactivity with other antiseptics poses a significant challenge when considering an alternative. We present a case of successful use of octenidine in a patient with confirmed chlorhexidine anaphylaxis, illustrating the low risk of systematic cross-sensitivity, as already suggested by ex vivo studies, and raising the possibility of its potential use as a reliable alternative.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.