Evidence map›Paper›PMID 41035823›Full record

SynthesisFrontiers in aging neuroscience2025

Microglia-associated research in Parkinson's disease: a bibliometric analysis.

Yan-Jun Chen, Ming-Rong Xie, Sheng-Qiang Zhou, Fang Liu

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in aging neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yan-Jun Chen *Graduate School, Hunan University of Chinese Medicine, Changsha, China.
Ming-Rong Xie *The First Clinical College, Nanjing University of Chinese Medicine, Nanjing, China.
Sheng-Qiang ZhouNational TCM Master Liu Zuyi Inheritance Studio, The Affiliated Hospital of Hunan Academy of Chinese Medicine, Changsha, China.
Fang LiuNational TCM Master Liu Zuyi Inheritance Studio, The Affiliated Hospital of Hunan Academy of Chinese Medicine, Changsha, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Parkinson's disease (PD) is a neurodegenerative disorder that predominantly affects the elderly. Evidence indicates that microglia-mediated neuroinflammation is recognized as one of the key mechanisms in PD. This study aims to analyze the key points, hotspots, and emerging frontiers in research related to PD and microglia. Method: Publications were obtained from the Web of Science and PubMed databases. VOSviewer and CiteSpace were used to generate visual representations and conduct numerical analyses of the dataset. Results: China and the United States were the leading contributors. Shanghai Jiao Tong University was the most active institution. The Conclusion: This study generated visual mappings of microglia and PD-related research. Neuroinflammation, a-syn, neurodegeneration, microglial activation, and oxidative stress represent major focuses and hotspots in this field. Gut microbiota and the NLRP3 inflammasome have rapidly attracted research attention and are likely to be key directions for future studies in the coming years.

Indexed as

gut microbiotamicroglianeuroinflammationNLRP3 inflammasomeParkinson’s disease

Identifiers

PMID41035823
PMCPMC12479480

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.