Evidence map›Paper›PMID 41035820›Full record

ArticleFrontiers in aging neuroscience2025

Effects of exercise-cognitive dual-task training on cognitive frailty in older adults: a randomized controlled trial.

Xiaoxing Lai, Hongwei Zhu, Yonghua Cai, Baoyu Chen, Yang Li, Hongdi Du, Liping Zhang, Wenwen Wang, Shuxian Li, Xiaopeng Huo

Abstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Effectiveness of mobile health interventions on physical activity management in frail older adults: a systematic review and meta-analysis.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2026
    Review
  3. Article
  4. Article
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiaoxing LaiDepartment of Neurology, Peking Union Medical College Hospital, Beijing, China.
Hongwei ZhuNursing Department, Peking Union Medical College Hospital, Beijing, China.
Yonghua CaiNursing Department, Peking Union Medical College Hospital, Beijing, China.
Baoyu ChenPeking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), Beijing, China.
Yang LiDepartment of Neurology, Peking Union Medical College Hospital, Beijing, China.
Hongdi DuDepartment of Health Care, Peking Union Medical College Hospital, Beijing, China.
Liping ZhangDepartment of Neurology, Peking Union Medical College Hospital, Beijing, China.
Wenwen WangDepartment of Neurology, Peking Union Medical College Hospital, Beijing, China.
Shuxian LiDepartment of Health Care, Peking Union Medical College Hospital, Beijing, China.
Xiaopeng HuoNursing Department, Peking Union Medical College Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aims to investigate the effects of exercise-cognitive dual-task training on frailty status, cognitive function, physical performance, and dual-task cognitive load in older adults with Cognitive frailty (CF) over a 16-week intervention period. Methods: This randomized controlled trial enrolled older adults with CF at community health service center in Chaoyang District, Beijing, between February and March 2024. Participants were randomly assigned to either the dual-task training group or the health education group in a 1:1 ratio. The dual-task training group received an exercise-cognitive dual-task training program, while the health education group received information on CF, including its symptoms, risk factors, and non-pharmacological prevention and treatment strategies. The primary outcomes were frailty status, while the secondary outcomes included cognitive function, balance and gait function, walking ability, and dual-task cognitive load. Results: A total of 72 participants (35 males) were enrolled, including 36 individuals (mean age: 74.81 ± 8.23 years, 17 males, mean BMI: 21.38 ± 2.83 kg/m Conclusion: Exercise-cognitive dual-task training may effectively improve frailty status, cognitive function, physical performance, and dual-task cognitive load in older adults with CF, suggesting its potential for broader application in this population. Clinical trial registration: http://www.chictr.org.cn/, ChiCTR2400080105.

Indexed as

cognitioncognitive frailtydual-task trainingexerciseolder adults

Identifiers

PMID41035820
PMCPMC12479488

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.