ArticleJournal of surgical case reports2025
A rare case of posterior fossa collision tumor involving low-grade astrocytoma and meningioma.
Article in Journal of surgical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
This case highlights a rare phenomenon, of two benign tumors, a low-grade astrocytoma, and meningioma, occurring simultaneously in the infratentorial compartment. This unique case seeks to add to the current literature on collision tumors. A 25-year-old female presented with a 9-month history of neck pain and right arm weakness. Imaging demonstrated a ring-enhancing cystic lesion in the posterior fossa, with solid enhancing extension into the spinal canal. The main differential diagnosis was an ependymoma. A suboccipital craniotomy, C1 laminectomy and C2-C4 laminoplasty, was performed and revealed two distinct tumor entities. Histopathology revealed that the cerebellar component was consistent with a low-grade astrocytoma and the extra-axial component was a meningioma. Coexisting tumors of different cell lineage and distinct borders, collision tumor, are very uncommon in clinical practice, with most cases diagnosed intra and post-operatively. A complete medical and genetic assessment is critical for the holistic management of these patients.
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