ArticleJournal of surgical case reports2025
Thyroidectomy in thyrotoxic crisis: is a euthyroid state required? A case series.
Article in Journal of surgical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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8 authors.
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Abstract
Thyrotoxic crisis is a life-threatening emergency where refractory cases require thyroidectomy. Achieving preoperative euthyroidism is difficult, and optimal surgical timing is debated. This study assessed outcomes of early thyroidectomy regardless of preoperative thyroid levels. A retrospective review included patients ≥18 years (2011-2020) meeting thyroid storm criteria (Japanese Thyroid Association and Burch-Wartofsky >25). Twelve women (median age 36) were included, primarily for medical treatment failure (83.3%). All received beta-blockers; median heart rate decreased from 110 to 76.5 bpm. All underwent total thyroidectomy with 100% parathyroid preservation. Complications included transient hypocalcemia and hypoparathyroidism (41.67% each). There was no mortality, thromboembolism, or need for renal replacement. Early thyroidectomy is a viable option for medically refractory thyrotoxic crisis. Strict heart rate control appears more critical than achieving preoperative euthyroidism, supporting its safety and feasibility.
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