Evidence map›Paper›PMID 41035686›Full record

ArticleiScience2025

Separable cognitive and motor decline tracked across adult life-span for goal-directed navigation.

Gian Luca Lancia, Marco D'Alessandro, Mattia Eluchans, Miguel Ibáñez-Berganza, Hugo J Spiers, Giovanni Pezzulo

Abstract read
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Adaptive planning depth in human problem-solving.Royal Society open science · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gian Luca LanciaInstitute of Cognitive Sciences and Technologies, National Research Council, Rome, Italy.
Marco D'AlessandroInstitute of Cognitive Sciences and Technologies, National Research Council, Rome, Italy.
Mattia EluchansInstitute of Cognitive Sciences and Technologies, National Research Council, Rome, Italy.
Miguel Ibáñez-BerganzaIMT School for Advanced Studies, Lucca, Italy.
Hugo J SpiersInstitute of Behavioural Neuroscience, Department of Experimental Psychology, University College London, London WC1E 6BT, UK.
Giovanni PezzuloInstitute of Cognitive Sciences and Technologies, National Research Council, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spatial navigation is a fundamental cognitive skill, yet our understanding of the strategies people employ in real-world navigation remains incomplete. By using a combination of behavioral and computational modeling approaches, we investigated navigation strategies - and their decline with age - in the Sea Hero Quest (SHQ) game, where participants controlled a boat to reach a series of goal locations, within different maps. We report three findings: First, participants favor goal-directed strategies over visibility-based strategies. Second, participants show signatures of sequential planning, both during memorization and navigation, as they show primacy effects. Third, our results show a significant age-related decline in navigation performance, which depends both on reduced motor skill and decreased cognitive strategy. Unexpectedly, the latter is not associated with a shift to visibility-based strategy or to an incorrect sequencing of goals. The models developed offer a framework for analyzing navigation and its links to neurodegenerative diseases in virtual environments.

Indexed as

cognitive neuroscienceComputer application in medicineneurosciencePsychology

Identifiers

PMID41035686
PMCPMC12481093

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.