Evidence map›Paper›PMID 41035660›Full record

ArticleEJHaem2025

Results From a UK Consensus via Delphi on Practical Considerations Surrounding Risk Assessment and Patient Monitoring for a Prompt Diagnosis of Severe Veno-Occlusive Disease (VOD) in Adults Post-HSCT.

A Clark, M Kenyon, A Pagliuca, R Shah, E Tholouli, J A Snowden

Abstract read
In one paragraph

Article in EJHaem, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

A ClarkQueen Elizabeth University Hospital Glasgow UK.
M KenyonKings College Hospital NHS Foundation Trust London UK.
A PagliucaKings College Hospital NHS Foundation Trust London UK.
R ShahUniversity College London Hospitals NHS Trust London UK.
E TholouliManchester Royal Infirmary, Manchester University NHS Foundation Trust Manchester UK.
J A SnowdenSheffield Teaching Hospitals NHS Foundation Trust Sheffield UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Veno-occlusive disease (VOD) is a life-threatening complication of haematopoietic stem cell transplantation (HSCT). The diagnosis remains challenging, with under recognition of the initial signs and symptoms potentially resulting in delayed diagnoses. The aim of this Delphi study is to establish a consensus regarding the optimal risk assessment and onward care of patients with VOD. Methods: The process employed a modified Delphi methodology. A steering group of six VOD experts working in the United Kingdom attended a virtual meeting in September 2023, developed 44 statements for testing. Respondents were offered a four-point Likert scale to indicate their level of agreement with each statement. Results: A total of 70 responses were received from healthcare providers working in the area of haematology and oncology in the United Kingdom. All statements achieved consensus. Overall, 82% of statements achieved ≥ 90% ( Conclusion: This modified Delphi process achieved consensus across all statements, allowing for a set of recommendations to be developed to support a consistent approach across the United Kingdom for the risk assessment and patient monitoring procedures for VOD post-HSCT.

Indexed as

Delphi consensuspatient monitoringrisk assessmentsinusoidal obstruction syndromestem cell transplantationveno‐occlusive disease

Identifiers

PMID41035660
PMCPMC12482513

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.