Evidence map›Paper›PMID 41035601›Full record

ArticleCureus2025

Severe Macrocytic Anemia in a Young Alcoholic Male: A Case Report.

Inês Ferreira, Inês Fiúza M Rua, Diogo Ramos, Sérgio Cabaço, André Valente

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Inês FerreiraInternal Medicine, Unidade Local de Saúde São José, Lisbon, PRT.
Inês Fiúza M RuaInternal Medicine, Unidade Local de Saúde São José, Lisbon, PRT.
Diogo RamosInternal Medicine, Unidade Local de Saúde São José, Lisbon, PRT.
Sérgio CabaçoInternal Medicine, Unidade Local de Saúde São José, Lisbon, PRT.
André ValenteInternal Medicine, Unidade Local de Saúde São José, Lisbon, PRT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin B12 and folate deficiency can lead to severe macrocytic anemia, apart from other consequences such as central and peripheral neurological symptoms. We report a case of a 23-year-old male presenting with severe pancytopenia, who was treated initially with red blood cell transfusions, intramuscular cyanocobalamin, and oral folate. The patient's laboratory parameters were normal after 50 days of therapy. During the investigation, alcohol use disorder (AUD) was identified and considered to be the cause of the vitamin deficiencies once other etiologies were excluded. While these vitamin deficiencies are more common among the elderly or malnourished populations, the high prevalence of AUD in young adults, mainly in men, remains an important cause and highlights the urgent need to be addressed both in individual cases and as part of public health measures.

Indexed as

alcohol use disorderfolatemacrocytic anaemiamegaloblastic anaemiapancytopeniavitamin b12

Identifiers

PMID41035601
PMCPMC12483574

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.