Evidence map›Paper›PMID 41035573›Full record

ReviewJRSM cardiovascular disease

Impact of climate change and air pollution on cardiovascular disease: A systematic review and meta-analysis protocol.

Zainab Haider Ejaz, Muhammad Fahad Maya, Fizzah Kazim, Zahira Amir Ali, Naureen Akber Ali, Adeel Khoja

Abstract readReview
In one paragraph

Review in JRSM cardiovascular disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zainab Haider EjazDepartment of Medicine, Aga Khan University, Karachi, Pakistan.
Muhammad Fahad MayaDepartment of Medicine, Ziauddin University, Karachi, Pakistan.ORCID https://orcid.org/0000-0003-1861-5313
Fizzah KazimDepartment of Medicine, Aga Khan University, Karachi, Pakistan.
Zahira Amir AliSchool of Nursing and Midwifery, Aga Khan University, Karachi, Pakistan.
Naureen Akber AliSchool of Nursing and Midwifery, Aga Khan University, Karachi, Pakistan.
Adeel KhojaDepartment of Medicine, Aga Khan University, Karachi, Pakistan.ORCID https://orcid.org/0000-0003-1513-408X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Climate change and increasing environmental pollution are emerging as significant threats to global health, notably through their impact on cardiovascular diseases (CVD). The World Health Organization (WHO) attributes millions of premature deaths annually to air pollution and extreme temperatures. Despite extensive research on air pollution and temperature extremes separately, their combined effects on cardiovascular health remain inadequately explored. Methods: We plan to conduct a systematic review and meta-analysis to assess the impact of climate change, including extremes of temperature and air pollution, on CVD. We will search PubMed, CINAHL, SCOPUS, ClinicalTrials.gov, and additional databases for studies published between August 12, 2019, and August 11, 2024. The review will include observational and quasi-experimental (pre and post-test) studies. Data extraction and quality assessment will be performed using EndNote, Rayyan.ai, and the National Heart, Lung, and Blood Institute (NHLBI) quality appraisal tool. The statistical analysis will be conducted using RevMan 5.4, with risk ratios, mean differences, and heterogeneity evaluated. Discussion: This review aims to synthesize evidence on how ambient air pollutants (PM Conclusion: By integrating the impacts of both climate change and air pollution on cardiovascular health, this review will provide comprehensive insights into the global health burden of CVD. The findings will inform public health strategies and interventions to mitigate the adverse effects of environmental factors on cardiovascular health.

Indexed as

air pollutioncardiovascular diseaseClimate changemeta-analysissystematic reviewtemperature extremes

Identifiers

PMID41035573
PMCPMC12480798

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.