Evidence map›Paper›PMID 41035435›Full record

ArticleOphthalmology science2026

Corneal Cross-Linking Induces Increased Corneal Refractive Index, Which Generates Measurement Error of Central Corneal Thickness.

Cynthia J Roberts, Austin DeGroff, Fernando M Nuñez, Andrew J Hendershot, Phillip T Yuhas

Erratum issuedAbstract read
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In one paragraph

Article in Ophthalmology science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Cynthia J RobertsDepartment of Ophthalmology & Visual Sciences, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio.
Austin DeGroffCollege of Optometry, The Ohio State University, Columbus, Ohio.
Fernando M NuñezCollege of Medicine, The Ohio State University, Columbus, Ohio.
Andrew J HendershotDepartment of Ophthalmology & Visual Sciences, College of Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio.
Phillip T YuhasCollege of Optometry, The Ohio State University, Columbus, Ohio.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study investigated the impact of a higher-than-expected corneal index of refraction (n Design: Theoretical analysis with prospective cohort study validation. Participants: Twenty-four eyes from 23 participants met the criteria for inclusion in data analysis. Methods: Two models were developed to represent side-view imaging with Scheimpflug geometry (model 1) and interferometric imaging in OCT (model 2). For both models, predicted CCT was calculated for various n Main Outcome Measures: Central corneal thickness and n Results: In side-view model 1, a negative relationship between predicted CCT and n Conclusions: The models indicate that an unknown increase in n Financial Disclosures: Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.

Indexed as

Central corneal thicknessCorneaCross-linkingKeratoconusRefractive index

Identifiers

PMID41035435
PMCPMC12481905

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.