Evidence map›Paper›PMID 41035434›Full record

ArticleJournal of exercise science and fitness2025

Replacement of leisure-time sedentary behavior with various physical activities and the risk of osteopenia and osteoporosis: evidence from the UK Biobank.

Zhuoyao Tian, Yuhua Gao, Biying Zhou, Zhenger Fang, Guangjun Zheng, Haofeng Zhang, Fudong He, Xia Chen, Mingliang Liu, Yuan Wei and 3 more

Abstract read
In one paragraph

Article in Journal of exercise science and fitness, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Zhuoyao TianKey Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, 510500, China.
Yuhua GaoSchool of Athletic Training, Guangzhou Sport University, Guangzhou, 510500, China.
Biying ZhouDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, China.
Zhenger FangDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, China.
Guangjun ZhengDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, China.
Haofeng ZhangGuangdong Provincial Engineering Research Center of Public Health Detection and Assessment, School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China.
Fudong HeGuangdong Provincial Engineering Research Center of Public Health Detection and Assessment, School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China.
Xia ChenDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, China.
Mingliang LiuDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou, China.
Yuan WeiKey Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, 510500, China.
Liangming LiKey Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, 510500, China.
Guang HaoGuangdong Provincial Engineering Research Center of Public Health Detection and Assessment, School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China.
Shuang PengKey Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, 510500, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Associations between sedentary behavior (SB) during leisure time and the risk of osteopenia and osteoporosis are inconclusive. We aimed to examine the impact of replacing sedentary time with equivalent durations of various physical activities on the risk of developing osteoporosis. Methods: This is a sub-study from the UK Biobank, in which heel bone mineral density (BMD) was measured via ultrasound densitometry among 193,600 participants. A Logistic regression model and an isotemporal substitution model were used in the analyses. Results: In this study, 52,430 osteopenia cases were recorded, of which 2443 were defined as osteoporosis. In comparison to participants with leisure-time SB < 5 h/day, the odds ratio (OR) of osteoporosis risk was 1.38 (95 % confidence interval [CI): 1.17-1.62) for >8 h/day. Replacing 30 min/day of leisure sedentary time with an equal time spent in the walk for pleasure was associated with a 3 % decrease of osteopenia risk and an 8 % decrease of osteoporosis risk, and replacing 3 min of leisure-time SB with an equal amount of strenuous sports was significantly associated with a 4 % reduction in the risk of osteoporosis and osteopenia (OR = 0.96, 95 %CI: 0.93-0.98 and OR = 0.96, 95 %CI: 0.96-0.97). Furthermore, strenuous sports as an alternative to SBs was significantly associated with a lower risk of osteopenia and osteoporosis, especially in participants achieving 1.5-2.5 h of summer light hours. Conclusion: Leisure-time SB was positively associated with the risk of osteopenia and osteoporosis. Replacing sedentary time with equal time of PA and achieving 1.5-2.5 h of summer sun exposure could be an effective way to reduce osteopenia and osteoporosis burden.

Indexed as

OsteoporosisPhysical activitySedentary behaviorSun exposure

Identifiers

PMID41035434
PMCPMC12483676

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.