ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2025
Bifurcations and phase transitions in the origins of life.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Review
- Evolution's hidden architecture: a non-lipschitz theory of creation and catastrophe.BMC ecology and evolution · 2025Article
- Neutral theory of cooperative dynamics.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Origins of life: the possible and the actual.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Article
- The Landscape of Synthetic Biology and Bioengineering in Spain.Engineering biologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The path towards the emergence of life in our biosphere involved several key events allowing for the persistence, reproduction and evolution of molecular systems. All these processes took place in a given environmental context and required both molecular diversity and the right non-equilibrium conditions to sustain and favour complex self-sustaining molecular networks capable of evolving by natural selection. Life is a process that departs from non-life in several ways and cannot be reduced to standard chemical reactions. Moreover, achieving higher levels of complexity required the emergence of novelties. How did that happen? Here, we review different case studies associated with the early origins of life in terms of phase transitions and bifurcations, using symmetry breaking and percolation as two central components. We discuss simple models that allow for understanding key steps regarding life origins, such as molecular chirality, the transition to the first replicators and cooperators, the problem of error thresholds and information loss and the potential for 'order for free' as the basis for the emergence of life.This article is part of the theme issue 'Origins of life: the possible and the actual'.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.