ArticleEuropean journal of medical research2025
Effects of surgery and CPAP on cardiovascular health in patients with obstructive sleep apnea.
Article in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to assess and compare the risks of cardiovascular disease and mortality in individuals with obstructive sleep apnea (OSA) undergoing treatment with either continuous positive airway pressure (CPAP) or upper airway surgery (UAS).
methodsUsing the TriNetX database, we identified 1,477,746 OSA patients between 2014 and 2019. In total 3638 matched pairs of patients were selected, based on their propensity scores, with one group having received UAS and the other having received CPAP therapy. The Cox proportional hazards models were used to compare the risk of major adverse cardiovascular events (MACEs) between the two groups. Subgroup analyses based on age, sex, race, and BMI categories were conducted to validate the findings.
resultsAfter propensity score matching, the UAS group had significantly lower risks of all-cause mortality (HR 0.45; 95% CI 0.33-0.59) and MACEs (HR 0.61; 95% CI 0.49-0.75) compared to the CPAP group. Subgroup analyses revealed that both male and female patients treated with UAS were associated with lower risks of all-cause mortality and MACEs. White individuals and those with BMI < 30 or ≥ 30, with age < 65 in the UAS group, consistently exhibited lower risks of all-cause mortality and MACEs.
conclusionsPatients with OSA receiving UAS were associated with lower risks of all-cause mortality and MACEs compared to those on CPAP. Subgroup analyses revealed variations in benefits, with lower risks of mortality and MACEs observed across different genders, age groups, racial backgrounds, and BMI categories within the UAS-treated population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.