Evidence map›Paper›PMID 41034954›Full record

ArticleBMC endocrine disorders2025

Aeromedical evaluation and successful return to flight in a military pilot with lingual thyroid: a case report and follow-up.

Pangmin Li, Liangchen Wang, Li Xiao, Lin Ding, Dandan Wang, Caizhe Yang, Di Zhu

Abstract readCase Reports
In one paragraph

Article in BMC endocrine disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pangmin LiDepartment of Endocrinology, Air Force Medical Center, Air Force Medical University, PLA, Beijing, 100142, China.
Liangchen WangDepartment of Endocrinology, Air Force Medical Center, Air Force Medical University, PLA, Beijing, 100142, China.
Li XiaoDepartment of Endocrinology, Air Force Medical Center, Air Force Medical University, PLA, Beijing, 100142, China.
Lin DingDepartment of Endocrinology, Air Force Medical Center, Air Force Medical University, PLA, Beijing, 100142, China.
Dandan WangDepartment of Endocrinology, Air Force Medical Center, Air Force Medical University, PLA, Beijing, 100142, China.
Caizhe YangDepartment of Endocrinology, Air Force Medical Center, Air Force Medical University, PLA, Beijing, 100142, China.
Di ZhuDepartment of Endocrinology, Air Force Medical Center, Air Force Medical University, PLA, Beijing, 100142, China. 373701696@qq.com.

Funding

Capital's Funds for Health Improvement and Research 2024-4-5122Young talent program of Air Force Medical Center 22BJQN005
6 · The paper itself

Abstract

backgroundLingual thyroid is a rare congenital anomaly resulting from the aberrant migration of thyroid tissue during embryonic development. Although frequently asymptomatic, its identification in military aircrew poses particular challenges given the rigorous standards of aeromedical certification. CASE PRESENTATION: A 37-year-old male military helicopter pilot was incidentally diagnosed with lingual thyroid during routine health screening. The patient remained asymptomatic throughout the clinical course. Comprehensive evaluations-including thyroid function tests, biochemical profiling, cervical magnetic resonance imaging, electronic laryngoscopy, radionuclide scanning, and portable sleep monitoring-confirmed the presence of a lingual thyroid with subclinical hypothyroidism. Imaging demonstrated the ectopic tissue at the tongue base to be the sole functioning thyroid gland. Levothyroxine therapy was initiated, resulting in normalization of thyroid hormone levels. Polysomnography was performed due to the anatomical location of the lesion and excluded obstructive sleep apnea or ventilatory compromise. Given the patient's strong motivation to resume flight duties, a multidisciplinary aeromedical evaluation was conducted. Based on clinical stability, absence of symptoms, and treatment response, the pilot was deemed aeromedically fit. Since June 2021, he has accumulated over 900 flight hours, with preserved thyroid function and no evidence of disease progression on longitudinal follow-up.

conclusionsTo the best of our knowledge, this represents the first documented case in China of a military pilot with lingual thyroid successfully certified for continued flying duties. This case suggests that congenital endocrine anomalies may be compatible with high-demand occupational roles in select cases, pending comprehensive individual evaluation and risk-based aeromedical assessment. It further supports the adoption of a risk-stratified, non-invasive management paradigm in aviation medicine, with implications for enhancing both flight safety and personnel retention.

Indexed as

Lingual ThyroidMilitary PersonnelPilotsReturn to WorkAdultAircraftFollow-Up StudiesHumansMalePrognosisAeromedical evaluation military aviation medicineLingual thyroidSubclinical hypothyroidism

Identifiers

PMID41034954
PMCPMC12486761

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.