ArticleBMC public health2025
Longitudinal association between social economic status and new-onset arthritis among middle-aged and elderly adults: evidence from the CHARLS cohort.
Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Spatiotemporal trends and socioeconomic drivers of hip-knee osteoarthritis burden in East Asia: a GBD-based modeling study (1990-2023).Clinical rheumatology · 2026Article
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3 authors.
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Abstract
backgroundArthritis represents a major global health burden, with social economic status (SES) emerging as a critical determinant. However, longitudinal evidence from Asian populations remains limited.
methodsThis prospective cohort study used China Health and Retirement Longitudinal Study (CHARLS) data, including 4,469 arthritis-free participants aged ≥ 45 years from baseline (2011) through 2018. SES was assessed using composite scores combining education and household wealth, categorized into four groups. New-onset arthritis was determined by self-reported physician diagnosis. Covariates included demographics, lifestyle factors, anthropometrics, and comorbidities. Multivariable logistic and Cox regression models estimated odds ratios (ORs) and hazard ratios (HRs) with 95% confidence intervals (CIs). Kaplan-Meier analysis estimated cumulative incidence with log-rank tests. Subgroup analyses examined effect modification by gender and age.
resultsDuring 7-year follow-up, 1,324 participants (29.6%) developed arthritis. In fully adjusted models, compared with low SES, upper-middle SES demonstrated reduced risk in both logistic (OR = 0.67, 95% CI: 0.55–0.82, P < 0.001) and Cox regression (HR = 0.71, 95% CI: 0.60–0.84, P < 0.001). High SES showed greater protection (OR = 0.41, 95% CI: 0.14-1.00; HR = 0.44, 95% CI: 0.18–1.08). Kaplan-Meier analysis showed cumulative incidence decreased across SES groups: 34.5% (low), 31.1% (low-middle), 23.5% (upper-middle), and 14.3% (high SES; log-rank P < 0.0001). Effects remained consistent across gender and age subgroups.
conclusionsHigher SES was independently associated with reduced arthritis risk among Chinese middle-aged and elderly adults, demonstrating a clear dose-response relationship. These findings support targeted prevention strategies for socioeconomically disadvantaged populations.
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