Evidence map›Paper›PMID 41034822›Full record

ArticleBMC geriatrics2025

Predictive value of Ishii test for sarcopenia in older patients with knee osteoarthritis.

Nanyan Li, Guangyuan Dong, Yun Lu, Pingjuan Tan, Jingchun Zhang, Qingzhao Liang, Shiqi Gong, Mengchao He, Yifei Wang, Lei Shi

Abstract read
In one paragraph

Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Nanyan Li *Southern Medical University, Guangzhou, Guangdong, P.R. China.
Guangyuan Dong *The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong, P.R. China.
Yun Lu *Shenzhen Pingle Orthopedic Hospital (Shenzhen Pingshan Traditional Chinese Medicine Hospital), Shenzhen, Guangdong, P.R. China.
Pingjuan TanShenzhen Pingle Orthopedic Hospital (Shenzhen Pingshan Traditional Chinese Medicine Hospital), Shenzhen, Guangdong, P.R. China.
Jingchun ZhangSouthern Medical University, Guangzhou, Guangdong, P.R. China.
Qingzhao LiangSouthern Medical University, Guangzhou, Guangdong, P.R. China.
Shiqi GongSouthern Medical University, Guangzhou, Guangdong, P.R. China.
Mengchao HeSouthern Medical University, Guangzhou, Guangdong, P.R. China.
Yifei WangSouthern Medical University, Guangzhou, Guangdong, P.R. China.
Lei ShiSouthern Medical University, Guangzhou, Guangdong, P.R. China. 35508897@qq.com.

Funding

Sanming Project of Medicine in Shenzhen, China No.SZZYSM202108013Traditional Chinese Medicine Bureau of Guangdong Province, China No.20241198
6 · The paper itself

Abstract

backgroundKnee osteoarthritis is becoming increasingly common, and the age-related decline in muscle mass or sarcopenia can exacerbate both conditions in a vicious cycle. Therefore, screening for sarcopenia is crucial for the management of both diseases. The Ishii score as an effective screening tool is currently widely used.

objectivesThis study aimed to validate the predictive effectiveness of the Ishii test in older adults with knee osteoarthritis patients, establish new cut-off value to assess its accuracy in predicting sarcopenia.

methodsA cross-sectional survey was conducted on 404 participants with knee osteoarthritis from China. Patients with sarcopenia were identified according to the 2019 criteria of the Asian Working Group for Sarcopenia. Social demographic variables, body composition, handgrip strength and calf circumference were collected and the Ishii score was calculated. The accuracy of the Ishii score test was determined by using indicators, including specificity, sensitivity, negative and positive predictive values, negative and positive likelihood ratios, Kappa value, Youden index, and receiver operating characteristic curve.

resultsThe Ishii test predicts sarcopenia at an AUC value of 0.85 for males, and at an AUC value of 0.84 for females. The cut-off value is over 108 for males and 119 for females, with the new cut-off value, the sensitivity, specificity, positive and negative predictive values, the kappa value or sarcopenia were 0.95, 0.66, 0.47, 0.98, 0.45 for males, and 0.91, 0.73, 0.47, 0.97,0.48 for females, respectively.

conclusionsThe study validated that the Ishii test can serve as a practical screening tool in community or clinical settings.

Indexed as

Osteoarthritis, KneeSarcopeniaAgedAged, 80 and overChinaCross-Sectional StudiesFemaleHand StrengthHumansMaleMiddle AgedPredictive Value of TestsIshiiKnee osteoarthritisOlder adultsSarcopenia

Identifiers

PMID41034822
PMCPMC12487035

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