Evidence map›Paper›PMID 41034807›Full record

Observational studyBMC cancer2025

Hearing, smell, and cognitive function after cancer treatment.

Stavros Potsakis, Juha Tapio Silvola, Ellen Karine Grov

Abstract readObservational Study
In one paragraph

Observational study in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Stavros PotsakisDepartment of Otorhinolaryngology, Akershus University Hospital, Sykehusveien 25, 1474, Akershus, Nordbyhagen, Norway. stavros.potsakis@ahus.no.ORCID http://orcid.org/0009-0005-6662-9447
Juha Tapio SilvolaDepartment of Otorhinolaryngology, Akershus University Hospital, Sykehusveien 25, 1474, Akershus, Nordbyhagen, Norway.ORCID http://orcid.org/0000-0001-7615-096X
Ellen Karine GrovFaculty of Health Sciences, Oslo Metropolitan University, Oslo, Norway.ORCID http://orcid.org/0000-0002-5347-8812

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study investigates the sensory and cognitive impact of cancer and its treatment, focusing on possible chemotherapy-induced hearing and olfactory impairment, and cognitive function. The primary aim is to evaluate the effectiveness and feasibility of an extended test battery for assessing sensory and cognitive function in cancer patients, providing foundational knowledge for a larger study. A secondary aim is to examine associations between chemotherapy types and sense-neurodegenerative function.

designAn observational cross-sectional, pilot study evaluated hearing, olfactory function, and cognitive function in first-line chemotherapy patients without prior brain injuries and ototoxic or otological histories. Self-reported outcomes on communication strategies, tinnitus and olfaction were collected. Data analysis applied descriptive statistics with t-tests, and Fisher´s exact tests to compare auditory, olfactory, and cognitive performance between treatment groups. STUDY SAMPLE: Thirteen cancer survivors (n = 13), six (n = 6) females and seven (n = 7) males who received two different types of chemotherapy.

resultsNo significant differences were observed between the chemotherapy groups in audiological and olfactory tests, cognitive assessment, or self-reported outcomes. However, among those receiving platinum-based chemotherapy, participants reported greater use of communication strategies in specific areas.

conclusionNo significant differences in hearing, olfactory, cognitive, and self-reported outcomes were found when examining cancer patients receiving two different chemotherapy types. The study highlights the need for advanced diagnostic tools to detect hearing, olfactory, and cognitive function in cancer survivors.

Indexed as

Antineoplastic AgentsCognitionHearingHearing LossNeoplasmsOlfaction DisordersSmellAdultAgedCancer SurvivorsCross-Sectional StudiesFemaleHumansMaleMiddle AgedPilot ProjectsAntineoplastic AgentsCancerCognitive assessmentHearing assessmentOlfactory assessmentPlatinum-based ChemotherapyTaxane-based chemotherapy

Identifiers

PMID41034807
PMCPMC12486504

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.