ArticleBMC psychiatry2025
Association between sleep duration, depression and cognitive decline trajectories: findings from a prospective cohort study in China.
Article in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Joint trajectories of sleep quality and cognitive function after acute ischemic stroke: a prospective cohort study using group-based dual trajectory modeling.Frontiers in medicine · 2026Article
- Association Between Sleep Quality and Cognitive Function in Patients with Hypertension in Rural Areas of Shanxi Province, China: The Chain Mediating Role of Anxiety and Depression.Psychology research and behavior management · 2026Article
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7 authors.
Funding
Abstract
objectiveThis study investigated the relationship between sleep duration and cognitive decline trajectories among Chinese adults with age ≥ 45. Additionally, it examined whether baseline depression symptoms mediated the association between sleep duration and cognitive decline trajectories.
methodsData came from the China Health and Retirement Longitudinal Study (CHARLS), a nationally survey of Chinese adults. Total sleep duration was grouped into shorter (≤ 6 h), normal (6-9 h), and longer (> 9 h). Nighttime sleep duration was categorized as shorter (≤ 6 h), normal (6-8 h), and longer (> 8 h). Daytime nap duration was classified into no nap, shorter (≤ 0.5 h), normal (0.5-1.5 h), and longer (> 1.5 h). Cognitive decline trajectories were identified using a group-based trajectory model (GBTM). Depression symptoms, measured by baseline depression scores, were included as a potential mediating variable. Multinomial logistic regression models were applied to analyze the association between sleep duration and cognitive trajectories.
resultsA total of 4,094 respondents were included. Participants were classified into three trajectory groups: high-level stable (n = 1,278, 31.2%), moderate-level slow-decline (n = 2,089, 51.0%), and low-level rapid-decline (n = 727, 17.8%). Compared to the stable group, shorter total sleep duration was associated with both rapid-decline (RRR:1.510; 95%CI:1.079,2.114) and slow-decline (RRR:1.466; 95%CI:1.145,1.877) cognitive trajectories. Similarly, shorter nighttime sleep duration was associated with both rapid-decline (RRR:1.572; 95%CI: 1.089,2.271) and slow-decline (RRR:1.480; 95%CI:1.129,1.939) cognitive trajectories compared to the stable group. Baseline depression symptoms did not mediate these relationships (P > 0.05).
conclusionsShorter total sleep duration (≤ 6 h) and shorter nighttime sleep duration (≤ 6 h) were significantly associated with cognitive decline trajectories. However, baseline depression symptoms did not mediate these relationships.
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