Evidence map›Paper›PMID 41034766›Full record

ArticleBMC public health2025

Disparities in COVID-19 mortality in the United States, 2020-2023.

Zain Ul Abidin, Joseph Thirumalareddy, Jaya S Gupta, Ali Bin Abdul Jabbar

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Where Inequities Emerge: Racial and Ethnic Differences Across the COVID-19 Hospitalization Continuum.International journal of environmental research and public health · 2026
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zain Ul AbidinDepartment of Medicine, Aga Khan University Medical College, Karachi, Pakistan.
Joseph ThirumalareddyDepartment of Medicine, Division of Internal Medicine, Creighton University School of Medicine, 7710 Mercy Road, Suite 301, Omaha, NE, 68124-2368, USA.
Jaya S GuptaDepartment of Medicine, Division of Internal Medicine, Creighton University School of Medicine, 7710 Mercy Road, Suite 301, Omaha, NE, 68124-2368, USA.
Ali Bin Abdul JabbarDepartment of Medicine, Division of Internal Medicine, Creighton University School of Medicine, 7710 Mercy Road, Suite 301, Omaha, NE, 68124-2368, USA. Alibinabduljabbar@creighton.edu.ORCID http://orcid.org/0000-0001-5145-8626

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe COVID-19 pandemic disproportionately affected various demographics and regions in the United States. Understanding disparities in COVID-19 mortality is essential for promoting health equity and guiding future responses.

objectiveTo examine demographic and regional disparities in age-adjusted and proportionate COVID-19 mortality in the US from 2020 to 2023. DESIGN, SETTING, AND

participantsIn this repeated cross-sectional study, data from the Centers for Disease Control and Prevention Wide-ranging Online Data for Epidemiologic Research (CDC WONDER) multiple causes of death database were used to analyze death certificates from 2020 to 2023 for COVID-19-related mortality among persons aged ≥ 15 years in the U.S.

main outcome measuresAge-adjusted mortality rate (AAMR) per 100,000 persons, Rate ratio (with 95% CI), and proportionate mortality of COVID-19, calculated using descriptive statistics.

resultsFrom 2020 to 2023, 1,167,362 (8.91%) of 13,098,787 total deaths in the U.S. were attributed to COVID-19. The AAMR peaked in 2021 at 147.0 (95% CI: 146.6-147.5) per 100,000, with 13.45% of all deaths related to COVID-19, decreasing to 23.1 (2.49%) by 2023. Males exhibited a 1.56-fold higher AAMR than females. Non-Hispanic (NH) American Indian/Alaska Native experienced the highest cumulative AAMR (154), followed by NH Native Hawaiian/Pacific Islander (124.2) and NH African American (123.9) populations. Hispanics had the highest proportionate mortality, with COVID-19 contributing to 23.55% of all deaths in 2021. The oldest age group (≥ 75 years) had the highest cumulative AAMR, 71.6 times higher compared to the youngest group (15-44 years), whereas the highest proportionate mortality was seen in middle-aged adults (45-74 years). Regionally, the Southern U.S. census region recorded the highest cumulative and annual AAMR, except for the Northeast, in 2020.

conclusionFrom 2020 to 2023, males, older adults, and racial/ethnic minority groups, notably NH AI/AN, NH NH/PI, NH African American, and Hispanic populations, experienced higher COVID-19 mortality. Regionally, the Southern U.S. Census region had the highest COVID-19 mortality, except for the Northeast, in 2020. These disparities underscore the importance of implementing equitable public health strategies and ensuring preparedness for future health crises. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

COVID-19Ethnic and Racial MinoritiesHealth Status DisparitiesAdolescentAdultAgedCross-Sectional StudiesEthnicityFemaleHumansMaleMiddle AgedUnited StatesYoung AdultCOVID-19Demographic disparitiesDisparitiesMortalityRegional disparitiesUnited states of america

Identifiers

PMID41034766
PMCPMC12487207

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.