Evidence map›Paper›PMID 41034639›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

Considerations on multiportal compartmental approach extended to the temporal fossa.

Enrico Fazio, Luca Gazzini, Giulia Gobbo, Monir Abousiam, Giovanni Giorgetti, Aurel Nebiaj, Giuseppe Nucera, Alberto Schreiber, Luca Calabrese

Abstract readCase ReportsLetter
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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Enrico FazioDepartment of Otorhinolaryngology-Head and Neck Surgery, Hospital of Bolzano (SABES-ASDAA), Teaching Hospital of the Paracelsus Medizinischen Privatuniversität (PMU), Bozen, Italy.ORCID 0000-0002-8892-7438
Luca GazziniDepartment of Otorhinolaryngology-Head and Neck Surgery, Hospital of Bolzano (SABES-ASDAA), Teaching Hospital of the Paracelsus Medizinischen Privatuniversität (PMU), Bozen, Italy.ORCID 0000-0002-5077-9847
Giulia GobboOtolaryngology-Head and Neck Surgery Department, University of Verona, 37134, Verona, Italy. ggobbo.md@gmail.com.ORCID 0009-0005-1056-1383
Monir AbousiamDepartment of Otorhinolaryngology-Head and Neck Surgery, Hospital of Bolzano (SABES-ASDAA), Teaching Hospital of the Paracelsus Medizinischen Privatuniversität (PMU), Bozen, Italy.ORCID 0000-0003-3685-510X
Giovanni GiorgettiDepartment of Otorhinolaryngology-Head and Neck Surgery, Hospital of Bolzano (SABES-ASDAA), Teaching Hospital of the Paracelsus Medizinischen Privatuniversität (PMU), Bozen, Italy.
Aurel NebiajDepartment of Otorhinolaryngology-Head and Neck Surgery, Hospital of Bolzano (SABES-ASDAA), Teaching Hospital of the Paracelsus Medizinischen Privatuniversität (PMU), Bozen, Italy.
Giuseppe NuceraDepartment of Otorhinolaryngology-Head and Neck Surgery, Hospital of Bolzano (SABES-ASDAA), Teaching Hospital of the Paracelsus Medizinischen Privatuniversität (PMU), Bozen, Italy.ORCID 0000-0002-2997-7195
Alberto SchreiberUnit of Otorhinolaryngology - Head and Neck Surgery, Hospital of Manerbio-Desenzano, ASST del Garda, Brescia, Italy.ORCID 0000-0002-1580-3928
Luca CalabreseDepartment of Otorhinolaryngology-Head and Neck Surgery, Hospital of Bolzano (SABES-ASDAA), Teaching Hospital of the Paracelsus Medizinischen Privatuniversität (PMU), Bozen, Italy.ORCID 0000-0001-6476-3689

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo illustrate the applicability of compartmental surgery (CS) principles in the radical management of advanced oral cavity squamous cell carcinoma (OSCC) involving the high infratemporal fossa (ITF), in cases where neoadjuvant therapy is not feasible.

methodsWe report a case of recurrent OSCC of the retromolar trigone with extensive involvement of the masticatory space, including the medial and lateral pterygoid, masseter, and temporalis muscles. A multiportal surgical approach was employed, integrating a transnasal endoscopic route with extended transoral and transcervical corridors. Surgical steps followed the CS concept, including en-bloc resection of tumour spread pathways and musculature insertions.

resultsRadical resection including the involved masticatory musculature and temporalis muscle insertions was achieved. The final histopathology confirmed advanced-stage disease (rpT4b N3b R0 L1 V0 pn1 G2), with complete macroscopic and microscopic tumour removal.

conclusionThis case supports the feasibility and oncologic efficacy of a CS-based multiportal approach in selected advanced OSCC involving the ITF. Further studies are needed to validate its role and define standardized protocols.

Indexed as

Carcinoma, Squamous CellInfratemporal FossaMouth NeoplasmsNeoplasm Recurrence, LocalHumansMaleMiddle AgedTemporal MuscleCompartmental surgeryInfratemporal fossaMasticatory spaceMultiportal approachOral squamous cell carcinoma

Identifiers

PMID41034639

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.