Evidence map›Paper›PMID 41034629›Full record

Reviewnpj antimicrobials and resistance2025

The butterfly effect: collateral damage and impacts of antimicrobial strategies on the oral microbiome.

Jason L Brown, William Johnston, Mark C Butcher, Mia Burleigh, Gordon Ramage

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in npj antimicrobials and resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jason L BrownOral Sciences Research Group, Glasgow Dental School, School of Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
William JohnstonOral Biofilm Research Group, Safeguarding Health through Infection Prevention (SHIP), School of Health and Life Sciences, Glasgow Caledonian University, Glasgow, UK.
Mark C ButcherOral Biofilm Research Group, Safeguarding Health through Infection Prevention (SHIP), School of Health and Life Sciences, Glasgow Caledonian University, Glasgow, UK.
Mia BurleighDivision of Sport, Exercise and Health, Sport and Physical Activity Research Institute, School of Health and Life Sciences, University of the West of Scotland, Glasgow, UK.
Gordon RamageOral Biofilm Research Group, Safeguarding Health through Infection Prevention (SHIP), School of Health and Life Sciences, Glasgow Caledonian University, Glasgow, UK. gordon.ramage@gcu.ac.uk.

Funding

Biotechnology and Biological Sciences Research Council BB/V509541/1
6 · The paper itself

Abstract

The oral cavity is a complex environment hosting diverse microbial biofilms on different surfaces, all immersed in saliva that enables recolonisation and spread. These microbial populations fluctuate with diet, hygiene, antimicrobials, and disease. While biofilm control measures aim to protect health, they may cause unintended effects, including antimicrobial resistance (AMR). Persistent resistant microbes reshape oral and systemic niches through ecological disruption and genetic adaptation, which may negatively impact human health.

Identifiers

PMID41034629
PMCPMC12489097

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.