Evidence map›Paper›PMID 41034610›Full record

ArticleNature methods2025

HippoMaps: multiscale cartography of human hippocampal organization.

Jordan DeKraker, Donna Gift Cabalo, Jessica Royer, Alexander Ngo, Ali R Khan, Bradley G Karat, Oualid Benkarim, Raul Rodriguez-Cruces, Birgit Frauscher, Raluca Pana and 12 more

Abstract read
In one paragraph

Article in Nature methods, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Multiscale characterization of the human claustrum from histology to MRI.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Quantitative MRI of the hippocampus reveals microstructural trajectories of aging and Alzheimer's disease pathology.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Jordan DeKrakerMcConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada. jordan.dekraker@mail.mcgill.ca.ORCID http://orcid.org/0000-0002-4093-0582
Donna Gift CabaloMcConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada.ORCID http://orcid.org/0000-0001-9568-1723
Jessica RoyerMcConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada.ORCID http://orcid.org/0000-0002-4448-8998
Alexander NgoMcConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada.
Ali R KhanRobarts Research Institute, University of Western Ontario, London, Ontario, Canada.
Bradley G KaratRobarts Research Institute, University of Western Ontario, London, Ontario, Canada.
Oualid BenkarimMcConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada.ORCID http://orcid.org/0000-0003-3922-7643
Raul Rodriguez-CrucesMcConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada.ORCID http://orcid.org/0000-0002-2917-1212
Birgit FrauscherDepartment of Neurology, Duke University Medical Center, Durham, NC, USA.
Raluca PanaMcConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada.
Justine Y HansenMcConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada.ORCID http://orcid.org/0000-0003-3142-7480
Bratislav MisicMcConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada.ORCID http://orcid.org/0000-0003-0307-2862
Sofie L ValkLise Meitner group Neurobiosocial, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
Jonathan C LauRobarts Research Institute, University of Western Ontario, London, Ontario, Canada.ORCID http://orcid.org/0000-0002-8452-8915
Matthias KirschnerDivision of Adult Psychiatry, Department of Psychiatry, University Hospitals of Geneva, Thonex, Switzerland.ORCID http://orcid.org/0000-0002-9486-1439
Andrea BernasconiMcConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada.
Neda BernasconiMcConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada.
Sascha E A MuenzingInstitute of Neuroscience and Medicine (INM-1:Structural and Functional Organisation of the Brain), Forschungszentrum Jülich, Jülich, Germany.
Markus AxerInstitute of Neuroscience and Medicine (INM-1:Structural and Functional Organisation of the Brain), Forschungszentrum Jülich, Jülich, Germany.ORCID http://orcid.org/0000-0001-5871-9331
Katrin AmuntsInstitute of Neuroscience and Medicine (INM-1:Structural and Functional Organisation of the Brain), Forschungszentrum Jülich, Jülich, Germany.ORCID http://orcid.org/0000-0001-5828-0867
Alan C Evans *McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada.ORCID http://orcid.org/0000-0003-3841-6098
Boris C Bernhardt *McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada. boris.bernhardt@mcgill.ca.ORCID http://orcid.org/0000-0001-9256-6041

Funding

Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada (NSERC Canadian Network for Research and Innovation in Machining Technology) 1304413Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada (NSERC Canadian Network for Research and Innovation in Machining Technology) 2023-05562Gouvernement du Canada | Instituts de Recherche en Santé du Canada | CIHR Skin Research Training Centre (Skin Research Training Centre) 175056Gouvernement du Canada | Instituts de Recherche en Santé du Canada | CIHR Skin Research Training Centre (Skin Research Training Centre) FDN-154298, PJT-174995, PJT-191853Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Swiss National Science Foundation) 219240
6 · The paper itself

Abstract

The hippocampus has a specialized microarchitecture, is situated at the nexus of multiple macroscale functional networks, contributes to numerous cognitive as well as affective processes and is highly susceptible to brain pathology across common disorders. These features make the hippocampus a model to understand how brain structure covaries with function, in both health and disease. Here we introduce HippoMaps, an open access toolbox and online data warehouse for the mapping and contextualization of subregional hippocampal data in the human brain ( http://hippomaps.readthedocs.io ). HippoMaps capitalizes on a unified hippocampal unfolding approach as well as shape intrinsic registration capabilities to allow for cross-participant and cross-modal data aggregation. We initialize this repository with a combination of hippocampal data spanning three-dimensional ex vivo histology, ex vivo 9.4-Tesla magnetic resonance imaging (MRI), as well as in vivo structural MRI and resting-state functional MRI obtained at 3 Tesla and 7 Tesla, together with intracranial encephalography recordings in patients with epilepsy. All code, data and tools are openly available online, with the aim of fostering further community contributions.

Indexed as

Brain MappingHippocampusHumansImage Processing, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance ImagingSoftware

Identifiers

PMID41034610
PMCPMC12510884

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.