ArticleNature2025
Monoclonal antibodies protect against pandrug-resistant Klebsiella pneumoniae.
Abstract read
In one paragraph
Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Convergent evolution of immune evasion in ESKAPE pathogens: A cross-pathogen architecture of conserved host-defense checkpoints.European journal of microbiology & immunology · 2026Review
- Monoclonal Antibodies Targeting Bacterial Infections: A Broad Review of the Field.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2026Review
- Carbapenemases: epidemiology, detection and management in a changing global landscape.JAC-antimicrobial resistance · 2026Review
- Human antibodies as emerging drugs for antimicrobial resistance.Trends in immunology · 2026Review
- Excessive C5 conversion prevents C9 polymerisation and subsequent MAC-dependent killing of Klebsiella pneumoniae.PLoS pathogens · 2026Article
- Global perspectives on Klebsiella epidemiology and biology: conference report on the KLEBS 2024 symposium.npj antimicrobials and resistance · 2026Article
- Transfer of anti-Klebsiella pneumoniae immunity following infection in mice is protective against lethal challenge in offspring.Scientific reports · 2026Article
- The TamA protein as a subunit vaccine improves immune protection against highly virulentCurrent research in microbial sciences · 2026Article
- Aggregation-Induced Emission Luminogens: Emerging Theranostic Platforms for Pulmonary Diseases.Luminescence : the journal of biological and chemical luminescence · 2026Review
- Avibactam-based combinations for the treatment of multidrug resistant Gram-negative bacilli infections.Le infezioni in medicina · 2026Review
- Extensively Drug-Resistant ST16Infection and drug resistance · 2026Article
- Adjuvant-driven epitope hierarchy correlates with the protective efficacy of FimA vaccine againstFrontiers in immunology · 2026Article
- Glycine restores the sensitivity to antibiotics in multidrug-resistant bacteria.Microbiology spectrum · 2024Article
- Klebsiella pneumoniae O-polysaccharide biosynthesis highlights the diverse organization of catalytic modules in ABC transporter-dependent glycan assembly.The Journal of biological chemistry · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
32 authors.
Emanuele Roscioli *Monoclonal Antibody Discovery (MAD) Lab, Fondazione Toscana Life Sciences, Siena, Italy.ORCID 0000-0003-4125-4632
Vittoria Zucconi Galli Fonseca *Monoclonal Antibody Discovery (MAD) Lab, Fondazione Toscana Life Sciences, Siena, Italy.ORCID 0000-0002-4593-2544
Soraya Soledad Bosch *Monoclonal Antibody Discovery (MAD) Lab, Fondazione Toscana Life Sciences, Siena, Italy.ORCID 0000-0003-1459-4463
Ida PacielloMonoclonal Antibody Discovery (MAD) Lab, Fondazione Toscana Life Sciences, Siena, Italy.
Giuseppe MaccariData Science for Health (DASCH) Lab, Fondazione Toscana Life Sciences, Siena, Italy.
Giulia CardinaliMonoclonal Antibody Discovery (MAD) Lab, Fondazione Toscana Life Sciences, Siena, Italy.
Giampiero BataniMonoclonal Antibody Discovery (MAD) Lab, Fondazione Toscana Life Sciences, Siena, Italy.
Samuele StazzoniMonoclonal Antibody Discovery (MAD) Lab, Fondazione Toscana Life Sciences, Siena, Italy.ORCID 0000-0002-1579-6895
Giusy TiseoDepartment of Clinical and Experimental Medicine, Infectious Diseases Unit, University of Pisa, Pisa, Italy.
Cesira GiordanoMicrobiology Unit, Azienda Universitaria Ospedaliera Pisana, Pisa, Italy.
Shen YuweiCenter for Anti-infective Research and Development, Hartford Hospital, Hartford, CT, US.
Laura CapocciaMonoclonal Antibody Discovery (MAD) Lab, Fondazione Toscana Life Sciences, Siena, Italy.ORCID 0009-0001-4172-1117
Dario CardamoneData Science for Health (DASCH) Lab, Fondazione Toscana Life Sciences, Siena, Italy.
Matteo RidelfiMonoclonal Antibody Discovery (MAD) Lab, Fondazione Toscana Life Sciences, Siena, Italy.
Marco TroisiMonoclonal Antibody Discovery (MAD) Lab, Fondazione Toscana Life Sciences, Siena, Italy.
Noemi ManganaroMonoclonal Antibody Discovery (MAD) Lab, Fondazione Toscana Life Sciences, Siena, Italy.ORCID 0000-0001-8512-4704
Chiara MugnainiMonoclonal Antibody Discovery (MAD) Lab, Fondazione Toscana Life Sciences, Siena, Italy.
Concetta De SantiMonoclonal Antibody Discovery (MAD) Lab, Fondazione Toscana Life Sciences, Siena, Italy.
Annalisa CiabattiniDepartment of Medical Biotechnologies, University of Siena, Siena, Italy.ORCID 0000-0002-4585-7783
Linda CerofoliniMagnetic Resonance Center (CERM), University of Florence, and Consorzio Interuniversitario Risonanze Magnetiche di Metalloproteine (CIRMMP), Sesto Fiorentino, Italy.
Marco FragaiMagnetic Resonance Center (CERM), University of Florence, and Consorzio Interuniversitario Risonanze Magnetiche di Metalloproteine (CIRMMP), Sesto Fiorentino, Italy.
Danilo LicastroAREA Science Park, Padriciano, Trieste, Italy.
Kelly WyresDepartment of Infectious Diseases, School of Translational Medicine, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0002-4033-6639
Laurent DortetINSERM, CEA, Center for Immunology of Viral, Auto-Immune, Hematological and Bacterial diseases (IMVA-HB/IDMIT/UMRS1184), Université Paris-Saclay, Fontenay-aux-Roses and Le Kremlin-Bicêtre, France.ORCID 0000-0001-6596-7384
Simona BarniniMicrobiology Unit, Azienda Universitaria Ospedaliera Pisana, Pisa, Italy.
David P NicolauCenter for Anti-infective Research and Development, Hartford Hospital, Hartford, CT, US.
Francesco MenichettiDepartment of Clinical and Experimental Medicine, Infectious Diseases Unit, University of Pisa, Pisa, Italy.
Marco FalconeDepartment of Clinical and Experimental Medicine, Infectious Diseases Unit, University of Pisa, Pisa, Italy.
Kamilia AbdelraoufCenter for Anti-infective Research and Development, Hartford Hospital, Hartford, CT, US.ORCID 0000-0003-2524-352X
Claudia SalaMonoclonal Antibody Discovery (MAD) Lab, Fondazione Toscana Life Sciences, Siena, Italy.
Anna KabanovaMonoclonal Antibody Discovery (MAD) Lab, Fondazione Toscana Life Sciences, Siena, Italy. a.kabanova@toscanalifesciences.org.ORCID 0000-0002-2077-472X
Rino RappuoliFondazione Biotecnopolo di Siena, Siena, Italy. rino.rappuoli@biotecnopolo.it.ORCID 0000-0002-8827-254X
Funding
No grant is acknowledged in the PubMed record.
Abstract
The 'silent pandemic' caused by antimicrobial resistance requires innovative therapeutic approaches. Human monoclonal antibodies (mAbs), which are among the most transformative and safe drugs in oncology
Indexed as
Antibodies, MonoclonalDrug Resistance, BacterialDrug Resistance, Multiple, BacterialKlebsiella InfectionsKlebsiella pneumoniaeAnimalsAnti-Bacterial AgentsBacteremiaBacterial CapsulesFemaleHumansMacrophagesMaleMiceO AntigensAnti-Bacterial AgentsAntibodies, MonoclonalO Antigens
Identifiers
PMID
41034577What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.