Evidence map›Paper›PMID 41034440›Full record

ArticleScientific reports2025

Evidence-based medical therapies for acute heart failure in Cameroon: a retrospective analysis of prescription patterns at Laquintinie Hospital, Douala, 2022-2024.

Djibrilla Siddikatou, Clovis Nkoke, Sidick Mouliom, Marie Solange Ndom, Edgar Mandeng Ma Linwa, Valérie Ndobo, Hermann Tsague, Sylvia Kotta, Esther Éléonore Ngo Linwa, Bronhilda Tifuh Takeh and 3 more

Abstract read
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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Djibrilla SiddikatouFaculty of Heath Sciences, University of Buea, Buea, Cameroon. djibrillasid@yahoo.fr.
Clovis NkokeFaculty of Heath Sciences, University of Buea, Buea, Cameroon.
Sidick MouliomFaculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon.
Marie Solange NdomFaculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon.
Edgar Mandeng Ma LinwaFaculty of Heath Sciences, University of Buea, Buea, Cameroon.
Valérie NdoboFaculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon.
Hermann TsagueFaculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon.
Sylvia KottaCardiology Unit, Internal Medicine Department, Hopital Laquintinie Douala, Douala, Cameroon.
Esther Éléonore Ngo LinwaFaculty of Heath Sciences, University of Bamenda, Bamenda, Cameroon.
Bronhilda Tifuh TakehFaculty of Heath Sciences, University of Buea, Buea, Cameroon.
Ba HamadouFaculty of Medicine and Biomedical Sciences, University of Garoua, Garoua, Cameroon.
Félicité KamdemFaculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon.
Anastase DzudieFaculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heart failure (HF) is a growing burden in sub-Saharan Africa, yet data on adherence to evidence-based medical therapy (EBMT) following the 2021 ESC/ACC guidelines remain scarce. This study explores patterns of EBMT prescriptions in a resource-limited African setting. We conducted a retrospective cohort study using medical records from patients hospitalised with acute HF at Laquintinie Hospital, Douala, Cameroon (2022-2024). The primary outcome was EBMT prescription at discharge, defined as at least Class IIa ESC/ACC recommendation irrespective of HF subtype and included medications like Renin-angiotensin aldosterone system (RAAS) inhibitors/Angiotensin Receptor-Neprilysin Inhibitors (ARNi), beta-blockers, mineralocorticoid receptor antagonists (MRAs), and sodium-glucose cotransporter-2 inhibitors (SGLT2i). Due to a limited sample size, analyses were primarily descriptive. Among 358 patients (median age 63 years, 50.6% female), hypertensive heart disease was the leading HF aetiology (33.0%) and HFrEF predominated (n = 192, 53.6%). EBMT at discharge was prescribed in patients. EBMT appeared to increase over the years (0% in 2022, 1.9% in 2023 and 17.5% in 2024; χ

Indexed as

Heart FailurePractice Patterns, Physicians'Acute DiseaseAdrenergic beta-AntagonistsAdultAgedAngiotensin Receptor AntagonistsCameroonEvidence-Based MedicineFemaleHumansMaleMiddle AgedMineralocorticoid Receptor AntagonistsRetrospective StudiesSodium-Glucose Transporter 2 InhibitorsAdrenergic beta-AntagonistsAngiotensin Receptor AntagonistsMineralocorticoid Receptor AntagonistsSodium-Glucose Transporter 2 InhibitorsCameroonEvidence-based medicationsGuideline-directed medical therapyHeart failureSGLT2 inhibitorsSub-Saharan Africa

Identifiers

PMID41034440
PMCPMC12489066

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.