Evidence map›Paper›PMID 41034406›Full record

ArticleScientific reports2025

Association of hemispheric retinal oxygen extraction and macular plexus-specific capillary density in moderate to advanced glaucomatous hemifield defect.

Martin Kallab, Nikolaus Hommer, Andreas Schlatter, Clemens Vass, René M Werkmeister, Doreen Schmidl, Leopold Schmetterer, Gerhard Garhöfer

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Martin KallabDepartment of Clinical Pharmacology, Medical University of Vienna, Währinger Gürtel 18-20, Vienna, 1090, Austria.
Nikolaus HommerDepartment of Clinical Pharmacology, Medical University of Vienna, Währinger Gürtel 18-20, Vienna, 1090, Austria.
Andreas SchlatterDepartment of Clinical Pharmacology, Medical University of Vienna, Währinger Gürtel 18-20, Vienna, 1090, Austria.
Clemens VassDepartment of Ophthalmology and Optometry, Medical University of Vienna, Vienna, Austria.
René M WerkmeisterCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.
Doreen SchmidlDepartment of Clinical Pharmacology, Medical University of Vienna, Währinger Gürtel 18-20, Vienna, 1090, Austria.
Leopold SchmettererDepartment of Clinical Pharmacology, Medical University of Vienna, Währinger Gürtel 18-20, Vienna, 1090, Austria.
Gerhard GarhöferDepartment of Clinical Pharmacology, Medical University of Vienna, Währinger Gürtel 18-20, Vienna, 1090, Austria. gerhard.garhoefer@meduniwien.ac.at.

Funding

Austrian Science Fund KLI 529Austrian Science Fund KLI 854
6 · The paper itself

Abstract

The aim was to characterize associations of the hemispheric retinal oxygen metabolism with glaucomatous damage and with retinal plexus-specific microvascular information in 35 hemispheres of 25 primary open-angle glaucoma patients with moderate to advanced glaucomatous hemifield defect. Mean deviations (MDs) were calculated using retinal ganglion cell (RGC) density-weighted, perimetric total deviations. RGC counts were modelled from retinal nerve fiber layer thickness. Using single-vessel blood flow (Doppler-OCT) and spectroscopic oxygen saturation, retinal blood flow (RBF) and oxygen extraction (extO

Indexed as

CapillariesGlaucoma, Open-AngleMacula LuteaOxygenRetinaRetinal VesselsAgedFemaleHumansMaleMiddle AgedOxygen ConsumptionRetinal Ganglion CellsTomography, Optical CoherenceOxygenOptical coherence tomography angiographyPOAGRetinal microcirculationRetinal oxygen extractionRetinal oxygen metabolism

Identifiers

PMID41034406
PMCPMC12488858

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.