ArticleNPJ Parkinson's disease2025
Percentile scores for the revised University of Pennsylvania Smell Identification Test for 16,972 individuals 60 years of age and older.
Article in NPJ Parkinson's disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05065060 (Parkinson's Progression Markers Initiative Online Study), which is not on this map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Parkinson's Progression Markers Initiative Online Study (PPMI Online)
Who cites it
2 citing papers in PubMed.
- Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker-Defined Synucleinopathy.Annals of clinical and translational neurology · 2026Article
- Predicting CSF α-Synuclein Seed Amplification Assay Status From Demographics and Clinical Data.Neurology open access · 2025Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The study goal was to use a very large study cohort to establish normative data for the revised UPSIT (UPSIT-R) and to compare the resultant percentiles to those of the original UPSIT. A second study was performed to compare the performance of these two tests in a cohort of persons with and without Parkinson's disease (PD). UPSIT-R percentiles were derived by age and sex in 16,972 volunteers. Non-parametric statistics were employed to compare the results of those with and without PD. UPSIT-R performance declined with increasing age; deficits were more pronounced in men than women. The magnitude of the difference between the original and revised test percentile scores differed by age and sex. Olfactory deficits in PD were confirmed on the UPSIT-R. This study provides normative data clinically useful for assessing the relative degree of dysfunction in persons 60 years of age and older using the UPSIT-R. Trial Registration Information: ClinicalTrials.gov NCT05065060 .
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Registered trials
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