Evidence map›Paper›PMID 41034267›Full record

ArticleNPJ Parkinson's disease2025

Assessing prevalence and risk factors for REM sleep behavior disorder among patients with inflammatory bowel disease.

Vijaya L Reddy, Zihan Chen, Sohail Dewain, Michelle Joo, Maya Bellomo, Erika Renkl, Sapna Patel, Emily Rivera, Laura Weisbein, Ahmed Ali and 2 more

Abstract read
In one paragraph

Article in NPJ Parkinson's disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Vijaya L ReddyDepartment Neurology, Yale School of Medicine, New Haven, CT, USA.
Zihan ChenYale School of Public Health, New Haven, CT, USA.
Sohail DewainDepartment Neurology, Yale School of Medicine, New Haven, CT, USA.
Michelle JooYale College, New Haven, CT, USA.
Maya BellomoYale College, New Haven, CT, USA.
Erika RenklDepartment Neurology, Yale School of Medicine, New Haven, CT, USA.
Sapna PatelDepartment Neurology, Yale School of Medicine, New Haven, CT, USA.
Emily RiveraDepartment Neurology, Yale School of Medicine, New Haven, CT, USA.
Laura WeisbeinCenter for Gastrointestinal Biology and Disease, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Ahmed AliDepartment Neurology, Yale School of Medicine, New Haven, CT, USA.
Michael D KappelmanDepartment of Pediatrics, University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Brian B KooDepartment Neurology, Yale School of Medicine, New Haven, CT, USA. brian.koo@yale.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

REM sleep behavior disorder (RBD) and inflammatory bowel disease (IBD) are associated with Parkinson's Disease. Using a cross-sectional design, we assessed RBD prevalence in IBD and controls. In total, 158 controls and 462 IBD patients completed IBD-related history questionnaires, the RBD Single-Question Screen (RBD1Q), and the RBD-Screening Questionnaire. RBD prevalence was compared using chi-squared testing. Logistic regression explored IBD-related factors associated with RBD (RBD1Q), adjusting for age, sex, race, and antidepressant usage. RBD prevalence was higher in IBD (14.1% vs. 5.1%; P = 0.002), driven by differences in women; 13.3% IBD and 1.0% controls had RBD. Among men, 16.0% IBD and 11.9% controls had RBD. IBD was associated with >threefold RBD odds (OR = 3.08, 95% CI [1.43, 6.62], P = 0.003). Men with RBD and IBD had higher IBD-related hospitalization rates than IBD males without RBD (95.2% vs. 63.0%; P = 0.004). RBD is more prevalent in IBD than in controls and is associated with severe IBD.

Identifiers

PMID41034267
PMCPMC12488973

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.