Evidence map›Paper›PMID 41034096›Full record

ArticleEndocrine journal2026

Sex-specific associations between annual kidney function changes and weight/waist changes in overweight Japanese: Japan Specific Health Checkup cohort.

Naoki Ozu, Jiro Takeuchi, Kiyoshi Asada, Kunihiro Yamagata, Kunitoshi Iseki, Toshiki Moriyama, Kazuhiko Tsuruya, Shouichi Fujimoto, Ichiei Narita, Tsuneo Konta and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Endocrine journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Naoki OzuDepartment of Clinical and Translational Science, Nara Medical University, Nara 634-8521, Japan.ORCID http://orcid.org/0009-0004-8790-587X
Jiro TakeuchiDepartment of Clinical and Translational Science, Nara Medical University, Nara 634-8521, Japan.ORCID http://orcid.org/0000-0002-4904-1693
Kiyoshi AsadaDepartment of Clinical and Translational Science, Nara Medical University, Nara 634-8521, Japan.ORCID http://orcid.org/0000-0002-4515-6047
Kunihiro YamagataThe Steering Committee for Japan Specific Health Checkups Study (J-SHC Study) Group, Fukushima 960-1295, Japan.ORCID http://orcid.org/0000-0002-7407-0410
Kunitoshi IsekiThe Steering Committee for Japan Specific Health Checkups Study (J-SHC Study) Group, Fukushima 960-1295, Japan.ORCID http://orcid.org/0000-0001-6624-0216
Toshiki MoriyamaThe Steering Committee for Japan Specific Health Checkups Study (J-SHC Study) Group, Fukushima 960-1295, Japan.ORCID http://orcid.org/0000-0002-9525-4999
Kazuhiko TsuruyaThe Steering Committee for Japan Specific Health Checkups Study (J-SHC Study) Group, Fukushima 960-1295, Japan.ORCID http://orcid.org/0000-0002-8390-2928
Shouichi FujimotoThe Steering Committee for Japan Specific Health Checkups Study (J-SHC Study) Group, Fukushima 960-1295, Japan.ORCID http://orcid.org/0000-0002-0025-4030
Ichiei NaritaThe Steering Committee for Japan Specific Health Checkups Study (J-SHC Study) Group, Fukushima 960-1295, Japan.ORCID http://orcid.org/0000-0001-7692-3096
Tsuneo KontaThe Steering Committee for Japan Specific Health Checkups Study (J-SHC Study) Group, Fukushima 960-1295, Japan.ORCID http://orcid.org/0000-0001-7681-6469
Masahide KondoThe Steering Committee for Japan Specific Health Checkups Study (J-SHC Study) Group, Fukushima 960-1295, Japan.ORCID http://orcid.org/0000-0001-6021-4375
Yugo ShibagakiThe Steering Committee for Japan Specific Health Checkups Study (J-SHC Study) Group, Fukushima 960-1295, Japan.ORCID http://orcid.org/0000-0002-8197-205X
Koichi AsahiThe Steering Committee for Japan Specific Health Checkups Study (J-SHC Study) Group, Fukushima 960-1295, Japan.ORCID http://orcid.org/0000-0002-4318-874X
Tsuyoshi WatanabeThe Steering Committee for Japan Specific Health Checkups Study (J-SHC Study) Group, Fukushima 960-1295, Japan.ORCID http://orcid.org/0000-0002-5189-9584
Masato KasaharaDepartment of Clinical and Translational Science, Nara Medical University, Nara 634-8521, Japan.ORCID http://orcid.org/0000-0002-1833-9075

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The impact of changes in obesity-related parameters on kidney functions is unclear. To evaluate the association of body weight (BW) and waist circumference (WC) changes with estimated glomerular filtration rate (eGFR) and proteinuria in obese individuals, we conducted retrospective analysis of the Japan Specific Health Checkup cohort of 664,926 participants (Japanese residents aged 40-74 years) from 2008 to 2011. Participants were classified into nine groups based on BW and WC changes from baseline. Sex differences were stratified. Generalized estimating equations were used to evaluate eGFR changes within each group and the effect of BW or WC changes on eGFR. In a similar manner, the impact of BW and WC changes on the incidence of proteinuria was measured. As a result, total of 20,326 participants with a body mass index of ≥25 kg/m

Indexed as

Body WeightGlomerular Filtration RateKidneyObesityOverweightWaist CircumferenceAdultAgedBody Mass IndexCohort StudiesEast Asian PeopleFemaleHumansJapanMaleMiddle AgedBody weightChronic kidney diseaseOverweightWaist circumference

Identifiers

PMID41034096
PMCPMC12819069

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.