Evidence map›Paper›PMID 41034094›Full record

Observational studyJournal of atherosclerosis and thrombosis2026

Prognostic Value of the HELT-E

Yoshiteru Okina, Tatsuya Saigusa, Yasushi Ueki, Masatoshi Minamisawa, Yushi Oyama, Naoto Hashizume, Daisuke Yokota, Minami Taki, Keisuke Senda, Tadamasa Wakabayashi and 13 more

Abstract readObservational StudyMulticenter StudyComparative Study
In one paragraph

Observational study in Journal of atherosclerosis and thrombosis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Predictive Value of the HELT-ECirculation reports · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Yoshiteru OkinaDepartment of Cardiovascular Medicine, Shinshu University School of Medicine.
Tatsuya SaigusaDepartment of Cardiovascular Medicine, Shinshu University School of Medicine.
Yasushi UekiDepartment of Cardiovascular Medicine, Shinshu University School of Medicine.
Masatoshi MinamisawaDepartment of Cardiovascular Medicine, Shinshu University School of Medicine.
Yushi OyamaDepartment of Cardiology, Shinonoi General Hospital.
Naoto HashizumeDepartment of Cardiology, Nagano red-cross Hospital.
Daisuke YokotaDepartment of Cardiology, Iida Hospital.
Minami TakiDepartment of Cardiology, Saku General Hospital.
Keisuke SendaDepartment of Cardiology, Aizawa Hospital.
Tadamasa WakabayashiDepartment of Cardiology, Suwa Central Hospital.
Koki FujimoriDepartment of Cardiology, Suwa red-cross Hospital.
Kenichi KarubeDepartment of Cardiology, Okaya City Hospital.
Takahiro SakaiDepartment of Cardiology, Ina Central Hospital.
Daisuke SunoharaDepartment of Cardiovascular Medicine, Shinshu University School of Medicine.
Kiu TanakaDepartment of Cardiovascular Medicine, Shinshu University School of Medicine.
Hidetomo NomiDepartment of Cardiovascular Medicine, Shinshu University School of Medicine.
Tadashi ItagakiDepartment of Cardiovascular Medicine, Shinshu University School of Medicine.
Soichiro EbisawaDepartment of Cardiovascular Medicine, Shinshu University School of Medicine.
Ayako OkadaDepartment of Cardiovascular Medicine, Shinshu University School of Medicine.
Tamon KatoDepartment of Cardiovascular Medicine, Shinshu University School of Medicine.
Takashi MiuraDepartment of Cardiology, Nagano Municipal Hospital.
Koichiro KuwaharaDepartment of Cardiovascular Medicine, Shinshu University School of Medicine.
I-PAD investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe HELT-E

methodsPatients undergoing endovascular therapy (EVT) for symptomatic LEAD between August 2015 and August 2016 were enrolled in the I-PAD NAGANO registry, a prospective, multicenter, observational registry. The primary endpoint was major adverse cardiovascular events (MACEs), defined as a composite of all-cause death, nonfatal myocardial infarction, and stroke at 5 years.

resultsA total of 366 patients were divided into low-risk (HELT-E

conclusionsThe HELT-E

Indexed as

Atrial FibrillationEndovascular ProceduresLower ExtremityPeripheral Arterial DiseaseStrokeAgedAged, 80 and overFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisProspective StudiesRegistriesRisk AssessmentEndovascular therapyHELT-E2S2 scoreLower extremity artery disease

Identifiers

PMID41034094
PMCPMC12979942

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.