Evidence map›Paper›PMID 41033904›Full record

ReviewSeminars in perinatology2026

Medical and surgical treatment of gastroesophageal reflux in the neonate.

Suzanna Hirsch

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Seminars in perinatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Suzanna HirschDivision of Gastroenterology, Hepatology & Nutrition, Aerodigestive Center, Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Boston, MA, USA. Electronic address: suzanna.hirsch@childrens.harvard.edu.

Funding

Non-invasive Biomarkers of Symptom Severity and Treatment Response in Pediatric Feeding DisordersK23DK137036 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI Suzanna Hirsch · 2023 to 2026
$776k
NIDDK NIH HHS K23 DK137036
6 · The paper itself

Abstract

Gastroesophageal reflux disease (GERD) is common in neonates, and a wide variety of symptoms have been attributed to reflux in this age group, including regurgitation, fussiness, and respiratory symptoms. Though the natural history of GERD is one of resolution in most infants, treatment may be needed when symptoms are particularly bothersome or associated with concerning medical complications. An array of management options exists for neonatal GERD, including both medical and surgical treatments. The goal of this review is to present an overview of nonpharmacologic, pharmacologic, and surgical GERD treatments and to review the available evidence on these treatments with a focus on research completed in the neonatal population.

Indexed as

FundoplicationGastroesophageal RefluxProton Pump InhibitorsHumansInfant, NewbornProton Pump InhibitorsAcid suppressionFundoplicationGastroesophageal reflux disease (GERD)Gastroesophageal reflux (GER)Milk protein allergyProkineticsThickening

Identifiers

PMID41033904
PMCPMC12541596

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.