Evidence map›Paper›PMID 41033691›Full record

ArticleBMJ mental health2025

Childhood exposure to particulate matter and nitrogen oxides and associations with mental health disorders in early adulthood: testing mediation by cognition in a UK longitudinal cohort study.

Thomas Canning, Louise Arseneault, Rachel M Latham, Joanne B Newbury, Aaron Reuben, Ioannis Bakolis, Helen L Fisher

Abstract read
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In one paragraph

Article in BMJ mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Thomas CanningDepartment of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID 0000-0001-9514-5701
Louise ArseneaultSocial, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Rachel M LathamESRC Centre for Society and Mental Health, King's College London, London, UK.
Joanne B NewburyPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Aaron ReubenDepartment of Psychology, University of Virginia, Charlottesville, Virginia, USA.
Ioannis BakolisDepartment of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Helen L FisherESRC Centre for Society and Mental Health, King's College London, London, UK helen.2.fisher@kcl.ac.uk.ORCID 0000-0003-4174-2126

Funding

Neuropsychological and genomic signatures of violence exposure in childhoodR01HD077482 · NICHD · DUKE UNIVERSITY · PI CASPI, AVSHALOM · 2013 to 2018
$2.8M
Evaluating neurodegenerative risk in middle-aged adults exposed to lead as childrenF31ES029358 · NIEHS · DUKE UNIVERSITY · PI REUBEN, AARON · 2018 to 2020
$113k
Medical Research Council (MRC) G1002190, MR/X010791/1NICHD NIH HHS R01 HD077482NIEHS NIH HHS F31 ES029358Wellcome TrustWellcome Trust 204823/Z/16/Z
6 · The paper itself

Abstract

backgroundLittle is known about the mechanisms underlying associations between air pollution exposure in childhood and mental health disorders in adulthood.

objectiveTo examine the prospective associations between age-10 air pollution exposure and age-18 mental health disorders and to test potential mediation by impaired cognition at age 12.

methodsWe used longitudinal observations of 1969 members of the Environmental Risk Study who were born across England and Wales in 1994-1995. Exposure to nitrogen dioxide, nitrogen oxides (NO

findingsHigher exposure to NO

conclusionsWe found no evidence that impaired cognition mediated associations between childhood residential exposure to NO CLINICAL IMPLICATIONS: Policies to reduce childhood exposure to NO

Indexed as

Air PollutantsAir PollutionEnvironmental ExposureMental DisordersNitrogen OxidesParticulate MatterAdolescentChildEnglandFemaleHumansLongitudinal StudiesMaleUnited KingdomWalesAir PollutantsNitrogen OxidesParticulate MatterAnxiety DisordersAttention Deficit and Disruptive Behavior DisordersDepressive DisorderMental Health

Identifiers

PMID41033691
PMCPMC12496056

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.