Evidence map›Paper›PMID 41033329›Full record

ArticleBiomedical physics & engineering express2025

Comparison of quantitative lung measures in low dose energy-integrating detector and photon-counting detector chest CT with an anthropomorphic phantom.

Natally AlArab, Marrissa J McIntosh, Junfeng Guo, Jarron Atha, Abhilash S Kizhakke Puliyakote, Jessica C Sieren, Eric Hoffman, Ehsan Abadi, Sean B Fain

Abstract readComparative Study
In one paragraph

Article in Biomedical physics & engineering express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Natally AlArabDepartment of Radiology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States of America.ORCID 0000-0002-8947-4100
Marrissa J McIntoshDepartment of Radiology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States of America.ORCID 0000-0003-2678-458X
Junfeng GuoDepartment of Radiology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States of America.
Jarron AthaDepartment of Radiology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States of America.
Abhilash S Kizhakke PuliyakoteDepartment of Radiology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States of America.ORCID 0000-0003-4541-0786
Jessica C SierenDepartment of Radiology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States of America.ORCID 0000-0002-1109-7886
Eric HoffmanDepartment of Radiology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States of America.ORCID 0000-0001-8456-9437
Ehsan AbadiDepartment of Radiology, Duke University, Durham NC, United States of America.ORCID 0000-0002-9123-5854
Sean B FainDepartment of Radiology, Carver College of Medicine, University of Iowa, Iowa City, IA, United States of America.ORCID 0000-0001-5461-0646

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Christopher K Laubenthal · 2000 to 2026
$70.0M
Using MRI To Visualize Regional Therapy Response In Idiopathic Pulmonary FibrosisR01HL126771 · NHLBI · DUKE UNIVERSITY · PI Bastiaan Driehuys · 2015 to 2026
$6.6M
Dynamic Imaging of Lung Ventilation and Perfusion Using CT and MRIR01HL169765 · NHLBI · UNIVERSITY OF IOWA · PI Sean Bedilion Fain · 2023 to 2026
$2.9M
Accuracy and Precision in CT Quantification of COPD Through Virtual Imaging TrialsR01HL155293 · NHLBI · DUKE UNIVERSITY · PI ABADI, EHSAN · 2021 to 2025
$2.2M
Ultra-low Dose, High Speed, High Resolution, Multispectral, Multi-Source MDCT ScaS10OD018526 · OD · UNIVERSITY OF IOWA · PI HOFFMAN, ERIC ALFRED · 2015 to 2015
$2.0M
NAEOTOM Alpha Photon-Counting CT ScannerS10OD034285 · OD · UNIVERSITY OF IOWA · PI HOFFMAN, ERIC ALFRED · 2024 to 2024
$2.0M
NCI NIH HHS P30 CA086862NHLBI NIH HHS R01 HL126771NHLBI NIH HHS R01 HL155293NHLBI NIH HHS R01 HL169765NIH HHS S10 OD018526NIH HHS S10 OD034285
6 · The paper itself

Abstract

Photon-counting detector (PCD) computed tomography (CT) promises improved resolution and contrast at reduced x-ray dose compared to energy-integrating detector (EID) CT. Our objective is to determine the parameters that achieve robust accuracy of quantitative measures in chest PCD-CT studies compared to quantitative EID-CT at low CT dose. The Kyoto LUNGMAN chest phantom with preserved lung tissue core and NIST-calibrated foam density standards (4-20 lbs.), and the COPD Lung Phantom II with six airways of various outer and inner diameters, were scanned using PCD-CT (NAEOTOM Alpha) and EID-CT (SOMATOM Force) with a target CT dose index (CTDI

Indexed as

LungPhantoms, ImagingPhotonsRadiation DosageRadiography, ThoracicTomography, X-Ray ComputedHumansPulmonary Disease, Chronic Obstructiveairwayscomparingdensitieskernelslow doselungPCD-CT

Identifiers

PMID41033329
PMCPMC13317018

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.