ReviewJournal of the American Society for Mass Spectrometry2025
Applications of DESI and DART Mass Spectrometry in Forensic Science.
Review in Journal of the American Society for Mass Spectrometry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
9 authors.
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Abstract
Ambient Mass Spectrometry (AMS) has revolutionized forensic analysis by enabling rapid and direct detection of chemical compounds on complex surfaces with minimal or no sample preparation. Among AMS techniques, desorption electrospray ionization (DESI) and direct analysis in real time (DART) mass spectrometry have emerged as powerful analytical tools due to their speed, sensitivity, and versatility. This review examines the major applications of DESI and DART in forensic science, including the detection of explosives, gunshot residue, illicit drugs, inks, biological fluids, and latent fingerprints. The principles of each technique are briefly discussed, followed by a comparative analysis of their advantages, limitations, and performances in various forensic scenarios. Recent developments, practical considerations for implementation, and future perspectives are also addressed, highlighting the growing impact of DESI and DART in real-time forensic investigations and evidence processing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.