Evidence map›Paper›PMID 41032726›Full record

ArticleJournal of chemical information and modeling2025

Davide Pietrafesa, Alice Romeo, Fabio Giovanni Tucci, Paola Fiorani, Federico Iacovelli, Mattia Falconi

Abstract read
In one paragraph

Article in Journal of chemical information and modeling, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Davide PietrafesaDepartment of Biology, University of Rome "Tor Vergata", Via della Ricerca Scientifica 1, 00133 Rome, Italy.ORCID 0009-0009-5154-6154
Alice RomeoDepartment of Biology, University of Rome "Tor Vergata", Via della Ricerca Scientifica 1, 00133 Rome, Italy.ORCID 0000-0001-6162-6814
Fabio Giovanni TucciDepartment of Biology, University of Rome "Tor Vergata", Via della Ricerca Scientifica 1, 00133 Rome, Italy.ORCID 0000-0002-6581-4684
Paola FioraniDepartment of Biology, University of Rome "Tor Vergata", Via della Ricerca Scientifica 1, 00133 Rome, Italy.ORCID 0000-0001-5409-2789
Federico IacovelliDepartment of Biology, University of Rome "Tor Vergata", Via della Ricerca Scientifica 1, 00133 Rome, Italy.ORCID 0000-0001-7511-6575
Mattia FalconiDepartment of Biology, University of Rome "Tor Vergata", Via della Ricerca Scientifica 1, 00133 Rome, Italy.ORCID 0000-0002-3990-4758

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The RNA-binding protein HuR (embryonic lethal abnormal vision-like protein 1) regulates mRNA stability and translation. HuR contains three RNA-recognition motifs (RRMs): the RRM1 and RRM2 confer high-affinity mRNA binding, while RRM3 mediates protein oligomerization. Although HuR is predominantly nuclear, cellular stimuli trigger its cytoplasmic translocation

Indexed as

ELAV-Like Protein 1Molecular Dynamics SimulationRNA, MessengerHumansModels, MolecularProtein BindingProtein ConformationELAVL1 protein, humanELAV-Like Protein 1RNA, Messenger

Identifiers

PMID41032726
PMCPMC12570136

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.