ArticleEuropean journal of applied physiology2026
The cross-over effects of unilateral resistance exercise in trained males and females.
Article in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo identify the cross-over effects on maximal contralateral force and muscle excitability following fatiguing unilateral resistance exercise of the lower and upper limbs in chronically trained participants.
methodsTwo crossover experiments using a within-subject, time-matched control design examined the contralateral responses on maximal force and muscle excitability in the elbow flexors (Experiment 1, resistance-trained, n = 20) and knee extensors (Experiment 2, endurance-trained, n = 23). Participants performed unilateral resistance exercise (four sets to task failure) while contralateral assessments were collected and compared to a no-exercise control condition.
resultsContralateral elbow flexor, but not knee extension, force declined over time (p < 0.01, ηₚ DISCUSSION: These findings suggest that acute unilateral resistance exercise does not compromise nor enhance contralateral force in trained individuals. However, alterations in maximal muscle excitability despite maintained force imply rapid contralateral neuromuscular adaptations within the input-output properties of muscle excitation and force. These results suggest differential susceptibility to cross-over effects across limbs and between sexes following unilateral resistance exercise.
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