Evidence map›Paper›PMID 41032063›Full record

ArticleMultidisciplinary respiratory medicine2025

Implementing oxygen saturation-based criteria for discontinuation of long-term oxygen therapy in nursing home residents with chronic -respiratory disease.

Gustavo Ferrer, Fernando Valerio-Pascua, César Alas-Pineda, Armando Cabrera Alonso, Agustin Yppolito, Maibetty Rodriguez, Diane Merrit, Viviane Manara, Kristhel Gaitán-Zambrano, Dennis J Pavón-Varela

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Article in Multidisciplinary respiratory medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Gustavo FerrerDepartment of Pulmonary and Critical Care Medicine, Aventura Hospital and Medical Center, Aventura, Florida, USA.ORCID 0000-0002-9271-5630
Fernando Valerio-PascuaDepartment of Critical Care, Hospital CEMESA, San Pedro Sula, Cortés, Honduras.ORCID 0000-0002-5880-7849
César Alas-PinedaDepartment of Analytics, Ferrer Pulmonary Institute, Miami, Florida, USA.ORCID 0000-0003-4183-9104
Armando Cabrera AlonsoDepartment of Pulmonary and Critical Care Medicine, Ferrer Pulmonary Institute, Miami, Florida, USA.
Agustin YppolitoDepartment of Pulmonary Research, Ferrer Pulmonary Institute, Miami, Florida, USA.
Maibetty RodriguezDepartment of Advanced Nursing Practice, Ferrer Pulmonary Institute, Miami, Florida, USA.
Diane MerritDepartment of Nursing Administration, Excelsior Group, Miami, Florida, USA.
Viviane ManaraDepartment of Healthcare Management, Ferrer Pulmonary Institute, Miami, Florida, USA.
Kristhel Gaitán-ZambranoDepartment of Research and Development, Dr. Ferrer Biopharma, Hallandale Beach, Florida, USA.ORCID 0000-0001-9124-194X
Dennis J Pavón-VarelaDepartment of Research and Development, Dr. Ferrer Biopharma, Hallandale Beach, Florida, USA.ORCID 0000-0003-4796-5902

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic respiratory diseases represent a significant global health burden, affecting millions of individuals. Long-term oxygen therapy (LTOT) has been a key treatment for patients with chronic hypoxemia due to these conditions, demonstrating benefits for survival and quality of life.

methodsAn observational, analytical, retrospective cohort study was conducted to evaluate clinical indicators for safely discontinuing oxygen therapy in 36 patients aged 50 years or older with chronic respiratory diseases residing in five nursing homes. Data included sociodemographic and clinical variables, such as comorbidities, oxygen saturation levels, and treatment details. A cohort of 36 nursing home residents with chronic respiratory diseases was analyzed.

resultsThe study revealed that 83.3% of patients had at least one comorbidity. Most patients (80.6%) used a nasal cannula for oxygen delivery, with a mean flow rate of 2.06 L/min. Approximately 80.6% achieved oxygen saturation >92% without supplemental oxygen. None of the patients who discontinued oxygen required readmission or oxygen reinstatement within the 4-week follow-up period.

conclusionsThis study provides preliminary evidence that achieving oxygen saturation >92% at rest or in exertion may represent a potential clinical indicator for safely discontinuing supplemental oxygen in patients with chronic respiratory diseases. However, given the retrospective design and small sample size, these findings should be interpreted cautiously and validated in larger, prospective studies.

Identifiers

PMID41032063
PMCPMC12558658

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