Evidence map›Paper›PMID 41031958›Full record

ArticleMolecular biology and evolution2025

Tandem Gene Clusters as Phylogenetic Anchors Reveal the Hidden History of Vertebrate Visual Opsins.

David Lagman, Christina A Bergqvist, Shigehiro Kuraku

Abstract read
In one paragraph

Article in Molecular biology and evolution, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

David LagmanDepartment of Medical Cell Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.ORCID 0000-0001-7600-5287
Christina A BergqvistDepartment of Medical Cell Biology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.ORCID 0009-0002-3983-9340
Shigehiro KurakuMolecular Life History Laboratory, National Institute of Genetics, Mishima, Japan.ORCID 0000-0003-1464-8388

Funding

JSPSKAKENHI 20H03269
6 · The paper itself

Abstract

The expansion of the visual opsin gene family was a crucial event in the diversification of vertebrate vision in evolution. Additional expansions in phototransduction-related genes facilitated the development of dim-light (rods) and color vision (cones). Sequence-based phylogeny and gene positions from extant jawed vertebrate genomes are insufficient to untangle the visual opsin duplications in early vertebrates. Additionally, jawless vertebrates share a visual opsin gene repertoire with jawed vertebrates which conflicts with recent findings of distinct whole-genome duplications in each lineage. To resolve these questions, we analyzed jawless vertebrate genomes, focusing on visual opsin genes. Our findings, based on chromosomal arrangements and relationships, confirm tandem duplications of visual opsins before the vertebrate radiation.

Indexed as

Multigene FamilyOpsinsVertebratesAnimalsEvolution, MolecularGene DuplicationPhylogenyOpsinsjawed vertebratesjawless vertebratestandem duplicationsvisual opsinswhole-genome duplications

Identifiers

PMID41031958
PMCPMC12486383

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.