Peripheral Neuromodulation for Treatment of Upper Extremity Complex Regional Pain Syndrome Following Peripherally Inserted Central Catheter Placement: A Case Report.

Mohammed A Alzarah, Veena M Do, Mark S Wallace, Rodney A Gabriel, Jeffrey L Chen

Abstract readCase Reports

In one paragraph

Article in Pain medicine case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

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0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mohammed A AlzarahUC San Diego Department of Anesthesiology, Center for Pain, La Jolla, CA.

Veena M DoUC San Diego Department of Anesthesiology, Center for Pain, La Jolla, CA.

Mark S WallaceUC San Diego Department of Anesthesiology, Center for Pain, La Jolla, CA.

Rodney A GabrielUC San Diego Department of Anesthesiology, Center for Pain, La Jolla, CA.

Jeffrey L ChenUC San Diego Department of Anesthesiology, Center for Pain, La Jolla, CA.

Funding

San Diego Biomedical Informatics Education & Research (SABER)T15LM011271 · NLM · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SHAMIM NEMATI · 2012 to 2026

$9.7M

NLM NIH HHS T15 LM011271

6 · The paper itself

Abstract

backgroundComplex regional pain syndrome (CRPS) is a chronic pain condition that typically affects distal extremities after an injury or noxious event, with symptoms disproportionate to the primary insult. We present the first successful use of a temporary peripheral nerve stimulator (PNS) followed by a permanent PNS system to treat CRPS Type 2 after failed responses to pharmacotherapies, trigger point injections, cervical epidural injections, and sympathetic nerve blocks. CASE REPORT: An 81-year-old patient developed CRPS Type 2 following a left antecubital peripherally inserted central catheter placement with left-hand paresthesia, edema, weakness, and skin color and temperature asymmetry. He achieved near-complete resolution of symptoms approximately 4 months after permanent PNS placement.

conclusionsThis case underscores the morbidity associated with iatrogenic complications, the challenges of managing CRPS when conventional treatments prove insufficient, and the necessity for further research to assess the effectiveness of PNS in improving both function and pain relief for CRPS patients.

Indexed as

Catheterization, PeripheralComplex Regional Pain SyndromesElectric Stimulation TherapyTranscutaneous Electric Nerve StimulationUpper ExtremityAged, 80 and overHumansMalecase reportComplex regional pain syndrome type 2peripheral nerve stimulationroutine procedure

Identifiers

PMID41031866

PMCPMC13178807

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.