Evidence map›Paper›PMID 41031838›Full record

ArticleMicrobiology spectrum2025

Polydextrose reduces the infection of

Lin Su, Huajie Zhao, Hafiz Muhammad Ishaq, Ningning Liu, Yalan Yang, Duan Li, Liang Liu, Chuansheng Wang, Fan Yang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lin SuHenan Collaborative Innovation Center of Prevention and Treatment of Mental Disorders, Henan Key Laboratory of Biological Psychiatry, The Second Affiliated Hospital of Xinxiang Medical University, Xinxiang, China.
Huajie ZhaoDepartment of Pathogenic Biology, School of Basic Medical Science, Xinxiang Medical University, Xinxiang, China.
Hafiz Muhammad IshaqFaculty of Veterinary and Animal Sciences, Muhammad Nawaz Shareef University of Agriculture, Multan, Pakistan.
Ningning LiuDepartment of Pathogenic Biology, School of Basic Medical Science, Xinxiang Medical University, Xinxiang, China.
Yalan YangDepartment of Pathogenic Biology, School of Basic Medical Science, Xinxiang Medical University, Xinxiang, China.
Duan LiDepartment of Pathogenic Biology, School of Basic Medical Science, Xinxiang Medical University, Xinxiang, China.
Liang LiuDepartment of Pathogenic Biology, School of Basic Medical Science, Xinxiang Medical University, Xinxiang, China.
Chuansheng WangHenan Collaborative Innovation Center of Prevention and Treatment of Mental Disorders, Henan Key Laboratory of Biological Psychiatry, The Second Affiliated Hospital of Xinxiang Medical University, Xinxiang, China.ORCID 0009-0000-1002-2391
Fan YangHenan Collaborative Innovation Center of Prevention and Treatment of Mental Disorders, Henan Key Laboratory of Biological Psychiatry, The Second Affiliated Hospital of Xinxiang Medical University, Xinxiang, China.ORCID 0000-0001-9582-1394

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polydextrose (PDX), as a prebiotic, is an extensively branched glucose polymer that can promote the growth of beneficial bacteria in the gut. Recent research indicates that PDX regulates intestinal function and supports immune balance, which helps to protect the gut from pathogenic bacteria. However, scarce research has been found that PDX prevents the host infection through the direct effects on the pathogen. In this study, we developed a mouse model infected with

Indexed as

Bacterial ProteinsGlucansKlebsiella InfectionsKlebsiella pneumoniaeAnimalsBiofilmsDisease Models, AnimalDown-RegulationFemaleGene Expression Regulation, BacterialHumansMiceBacterial ProteinsGlucanspolydextroseadhesionbiofilminterspecies and intraspecies competitionK. pneumoniaepolydextroseTamA

Identifiers

PMID41031838
PMCPMC12584633

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.