Evidence map›Paper›PMID 41031815›Full record

ArticleMicrobiology spectrum2025

Discrepancies in isoniazid susceptibility profiles: Bactec MGIT 960-resistant but GenoType MTBDR

Zhenhua Chen, Peilei Hu, Jingwei Guo, Jue Wang, Binbin Liu, Yunhong Tan

Abstract read
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhenhua Chen *Clinical Laboratory, Hunan Chest Hospital, Changsha, People's Republic of China.ORCID 0009-0001-7183-5262
Peilei Hu *Clinical Laboratory, Hunan Chest Hospital, Changsha, People's Republic of China.
Jingwei GuoClinical Laboratory, Hunan Chest Hospital, Changsha, People's Republic of China.
Jue WangClinical Laboratory, Hunan Chest Hospital, Changsha, People's Republic of China.
Binbin LiuClinical Laboratory, Hunan Chest Hospital, Changsha, People's Republic of China.ORCID 0000-0001-9698-6991
Yunhong TanClinical Laboratory, Hunan Chest Hospital, Changsha, People's Republic of China.ORCID 0009-0005-1027-7059

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Discordant drug susceptibility testing (DST) results between the Bactec MGIT 960 system (MGIT) and the GenoType MTBDR IMPORTANCE: This study addresses a critical challenge in drug susceptibility testing (DST): the discrepancies in DST results for isoniazid (INH) between the Bactec MGIT 960 system and the GenoType MTBDR

Indexed as

Antitubercular AgentsDrug Resistance, BacterialIsoniazidMycobacterium tuberculosisBacterial ProteinsChinaGenotypeHumansMicrobial Sensitivity TestsMutationTuberculosis, Multidrug-ResistantWhole Genome SequencingAntitubercular AgentsBacterial ProteinsIsoniazidBactec MGIT 960drug susceptibility testingGenotype MTBDRplusisoniazidMycobacterium tuberculosiswhole-genome sequencing

Identifiers

PMID41031815
PMCPMC12584712

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.